Protein Alignment Cdk8 and cdk20

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_009302023.1
• Gene: cdk20 / 494112
• ZFINID: ZDB-GENE-041212-84
• Length: 359
• Species: Danio rerio
• Alignment Length: 376
• Identity: 122/376 - (32%)
• Similarity: 190/376 - (50%)
• Gaps: 59/376 - (15%)

  Fly     7 MKTQIERTKVE-----DLFNYEGCKVGRGTYGHVYKAKWKETSDG---KEYALKQIDGTGLSMSA 63
            |..|:..::|.     |.::..| ::|.|.:|.|:|||..||.:.   |:.||:::: .|:...|
Zfish     1 MLIQLATSRVTVSIGMDQYSILG-RIGEGAHGIVFKAKHIETGETVALKKVALRRLE-DGIPNQA 63

  Fly    64 CREIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMV 128
            .|||..|:|::....:..::....|....| |:.:|...||..:|:        ..|..:....|
Zfish    64 LREIKALQEIEDNQYVVKLKDVFPHGTGFV-LVFEYMLSDLSEVIR--------NSQRPLTASQV 119

  Fly   129 KSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPV 193
            ||.:..:|.|:.:.|.|.::||||||||:|:    :..|.:||||.|.||||:.....|  ....
Zfish   120 KSYMMMLLKGVAFCHENSIMHRDLKPANLLI----SSTGHLKIADFGLARLFSNEGDRL--YSHQ 178

  Fly   194 VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNV 258
            |.|.||||||||.|||.|.:.:|:||:||||.|||.:.|:|. .:.||        :||..:..|
Zfish   179 VATRWYRAPELLYGARKYDEGVDLWAVGCIFGELLNNSPLFP-GENDI--------EQLCCVLRV 234

  Fly   259 MGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDS--KAFHLLQKLLLMDPN 321
            :|.|..|.|.:|.::|:::.:|  ||.:        ..:...:|.||:  :|..||:|.|:....
Zfish   235 LGTPNQKVWPEITELPDYNKIT--FKEN--------PPIPLEEIVPDTSPQAVDLLKKFLVYPSK 289

  Fly   322 KRITSEQAMQDQYFQEEPQPTQDVFAGCPIP-----------YPKREFLTD 361
            :||::.||:...||..:|.|..  .:..|||           .|..||..|
Zfish   290 QRISARQALLHPYFFTDPLPAH--HSELPIPQRGGKHSRQRMQPPHEFTVD 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	107/320 (33%)
cdk20	XP_009302023.1	STKc_CCRK	18..304	CDD:270826	108/321 (34%)