Protein Alignment Cdk8 and cdk11b

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_009302607.1
• Gene: cdk11b / 494103
• ZFINID: ZDB-GENE-041212-74
• Length: 807
• Species: Danio rerio
• Alignment Length: 376
• Identity: 127/376 - (33%)
• Similarity: 206/376 - (54%)
• Gaps: 65/376 - (17%)

  Fly    23 EGC----------KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLREL 73
            :||          ::..||||.||:||.|:|.:  ..|||::    :..|..:::.|||..:.:.
Zfish   442 QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDE--IVALKRLKMEKEKEGFPITSLREINTILKA 504

  Fly    74 KHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDG 138
            :|.|::|:..:.:..|..|::::::|.||||       ::...|.||..:| |.||:|:.|:|.|
Zfish   505 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDL-------KSLMETMKQPFLP-GEVKTLMIQLLRG 561

  Fly   139 IHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPE 203
            :.:||.||:||||||.:|:|:    :.:|.:||.|.|.||.:.:||||..   |||||.|||:|:
Zfish   562 VRHLHDNWILHRDLKTSNLLL----SHKGILKIGDFGLAREYGSPLKPYT---PVVVTLWYRSPD 619

  Fly   204 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWE 268
            |||||:.|:.|:|:|::||||.||||.:|:|..:.|         .||:::||..:|.|.:|.|.
Zfish   620 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSE---------IDQINKIFKDLGSPSEKIWP 675

  Fly   269 DIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQ 333
            ...::|.       .|:.|::........:|.......:.|.|:.|.|...|.|||::::|::.:
Zfish   676 GYSELPA-------VKKMTFTEYPYNNLRKRFGALLSDQGFDLMNKFLTYCPAKRISADEALKHE 733

  Fly   334 YFQEEPQPTQ-DVFAGCP---------------IPYPKREF--LTDDDQED 366
            ||:|.|.|.. .:|...|               .|...::|  |.|||.:|
Zfish   734 YFRESPLPIDPSMFPTWPAKSEQQRVKRGTSPRAPEGGQDFSQLGDDDLKD 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	113/325 (35%)
cdk11b	XP_009302607.1	STKc_CDC2L1	444..735	CDD:173741	112/323 (35%)