Protein Alignment Cdk8 and cdk2

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_998571.1
• Gene: cdk2 / 406715
• ZFINID: ZDB-GENE-040426-2741
• Length: 298
• Species: Danio rerio
• Alignment Length: 333
• Identity: 123/333 - (36%)
• Similarity: 183/333 - (54%)
• Gaps: 52/333 - (15%)

  Fly    15 KVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKH 75
            |||        |:|.||||.|||||.|.|  |:..|||:|    :..|:..:|.|||:||:||.|
Zfish     6 KVE--------KIGEGTYGVVYKAKNKVT--GETVALKKIRLDTETEGVPSTAIREISLLKELNH 60

  Fly    76 QNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIH 140
            .|::.|..|.  |.:.|::|:.::...||...:.     ..:...:.:|  :|||.|:|:|.|:.
Zfish    61 PNIVKLRDVI--HTENKLYLVFEFLHQDLKRFMD-----STSVSGISLP--LVKSYLFQLLQGLA 116

  Fly   141 YLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELL 205
            :.||:.||||||||.|:|:    |.:|.:|:||.|.||.|..|::....   .|||.||||||:|
Zfish   117 FCHSHRVLHRDLKPQNLLI----NAQGEIKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEIL 174

  Fly   206 LGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDI 270
            ||.::|:.|:|||::||||||::|...:|....|         .|||.|||..:|.|.:..|..:
Zfish   175 LGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSE---------IDQLFRIFRTLGTPDESIWPGV 230

  Fly   271 KKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKP--DSKAFHLLQKLLLMDPNKRITSEQAMQDQ 333
            ..||::......:.|...|           |:.|  |.....||.::|..||||||:::.|:..:
Zfish   231 TSMPDYKPSFPKWARQDLS-----------KVVPPLDEDGRDLLGQMLTYDPNKRISAKNALVHR 284

  Fly   334 YFQEEPQP 341
            :|::...|
Zfish   285 FFRDVTMP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	118/321 (37%)
cdk2	NP_998571.1	STKc_CDK2_3	3..286	CDD:270844	121/325 (37%)