Protein Alignment Cdk8 and cdk1

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_988908.1
• Gene: cdk1 / 394503
• XenbaseID: XB-GENE-482750
• Length: 302
• Species: Xenopus tropicalis
• Alignment Length: 338
• Identity: 122/338 - (36%)
• Similarity: 183/338 - (54%)
• Gaps: 63/338 - (18%)

  Fly    12 ERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRE 72
            |.||:|        |:|.||||.|||.:.|.|  |:..|:|:|    :..|:..:|.|||:||:|
 Frog     3 EYTKIE--------KIGEGTYGVVYKGRHKAT--GQVVAMKKIRLENEEEGVPSTAIREISLLKE 57

  Fly    73 LKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQV-VVPRG------MVKS 130
            |:|.|::.|:.|.:  .|.:::|:.::...||             ||.: .:|.|      :|||
 Frog    58 LQHPNIVCLLDVLM--QDSRLYLIFEFLSMDL-------------KKYLDSIPSGQYIDTMLVKS 107

  Fly   131 LLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVV 195
            .|||||.||.:.||..||||||||.|:|:    :.:|.:|:||.|.||.|..|::....   .||
 Frog   108 YLYQILQGIVFCHSRRVLHRDLKPQNLLI----DSKGVIKLADFGLARAFGIPVRVYTH---EVV 165

  Fly   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMG 260
            |.||||||:|||:..|:..:|:|:||.||||:.|.:|:||...|         .|||.|||..:|
 Frog   166 TLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSE---------IDQLFRIFRALG 221

  Fly   261 FPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKP-DSKAFHLLQKLLLMDPNKRI 324
            .|.::.|.:::.:.::......:|....|.          .:|. |.....||.|:|:.||.|||
 Frog   222 TPNNEVWPEVESLQDYKNTFPKWKGGNLSA----------NVKNIDKDGLDLLSKMLIYDPAKRI 276

  Fly   325 TSEQAMQDQYFQE 337
            ::.:|:...||.:
 Frog   277 SARKALLHPYFDD 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	116/327 (35%)
cdk1	NP_988908.1	STKc_CDK1_euk	3..287	CDD:270845	120/334 (36%)