Protein Alignment Cdk8 and Cdk9

DIOPT Version :9

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Alignment Length: 421
• Identity: 129/421 - (30%)
• Similarity: 196/421 - (46%)
• Gaps: 81/421 - (19%)

  Fly     2 DYDFKMKTQIERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMS 62
            ||||....  |..|.|.:     .|:|:||:|.|:||:.|: .:.|..|:|::    :..|..::
  Fly    38 DYDFPYCD--ESNKYEKV-----AKIGQGTFGEVFKAREKK-GNKKFVAMKKVLMDNEKEGFPIT 94

  Fly    63 ACREIALLRELKHQNVITLIRV-----FLSHNDRKVFLLI-DYAEHDLWHIIKFHRAAKATKKQV 121
            |.|||.:|:.|||:||:.||.:     ..::..|..|.|: |:.||||        |...:...|
  Fly    95 ALREIRILQLLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDL--------AGLLSNMNV 151

  Fly   122 VVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKP 186
            ....|.:|.::.|:|:|::|:|||.:||||:|.||:|:    .:.|.:|:||.|.||.|:.|...
  Fly   152 KFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLI----TKHGILKLADFGLARAFSIPKNE 212

  Fly   187 LAD-LDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHD 250
            ..: ....|||.|||.||||||.|:|...:|:|..|||.||:.|..||.....|         ..
  Fly   213 SKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTE---------QQ 268

  Fly   251 QLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMER---HKIKP---DSKAF 309
            ||..|..:.|......|..::::            ..|.:..|.|..:|   .:::|   |....
  Fly   269 QLTFISQLCGSFTPDVWPGVEEL------------ELYKSIELPKNQKRRVKERLRPYVKDQTGC 321

  Fly   310 HLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQ 374
            .||.|||.:||.|||.::.|:...:|..:|.|:                       |.|....|.
  Fly   322 DLLDKLLTLDPKKRIDADTALNHDFFWTDPMPS-----------------------DLSKMLSQH 363

  Fly   375 QQQQQQQQQQQQQQQQQQQQQQQQQQMNAEP 405
            .|...:...|.::..|.:...||...||.:|
  Fly   364 LQSMFEYLAQPRRSNQMRNYHQQLTTMNQKP 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	108/332 (33%)
		S_TKc	22..335	CDD:214567	108/329 (33%)
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	115/349 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940