Protein Alignment Cdk8 and Cdk5

DIOPT Version :9

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 119/322 - (36%)
• Similarity: 179/322 - (55%)
• Gaps: 52/322 - (16%)

  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86
            |:|.||||.|:|.:.::|.:  ..|||::    |..|:..||.|||.||:||||:|::.||.|.
  Fly     9 KIGEGTYGTVFKGRNRDTME--IVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVL- 70

  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQV-----VVPRGMVKSLLYQILDGIHYLHSNW 146
             |:|:|:.|:.::.:.||             ||..     .:...:.:|.:.|:|.|:.:.||:.
  Fly    71 -HSDKKLTLVFEHCDQDL-------------KKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHN 121

  Fly   147 VLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHY 211
            ||||||||.|:|:    |:.|.:|:||.|.||.|..|:|..:   ..|||.|||.|::|.||:.|
  Fly   122 VLHRDLKPQNLLI----NKNGELKLADFGLARAFGIPVKCYS---AEVVTLWYRPPDVLFGAKLY 179

  Fly   212 TKAIDIWAIGCIFAELL-TSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPE 275
            |.:||:|:.|||.|||. ...|:|  ...|:.       |||.:||.|:|.|.:..|..:..:.:
  Fly   180 TTSIDMWSAGCILAELADAGRPLF--PGSDVL-------DQLMKIFRVLGTPNEDSWPGVSHLSD 235

  Fly   276 HHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQE 337
            :..|.     |..:..|.::.:.|    .:||...||||||:..||:||::|.|||..||.:
  Fly   236 YVALP-----SFPAITSWSQLVPR----LNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	117/318 (37%)
		S_TKc	22..335	CDD:214567	117/318 (37%)
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	119/320 (37%)
		STKc_CDK5	3..286	CDD:143344	117/318 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442416
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940