Protein Alignment Cdk8 and Cdk2

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001424913.1
• Gene: Cdk2 / 362817
• RGDID: 70486
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 379
• Identity: 131/379 - (34%)
• Similarity: 188/379 - (49%)
• Gaps: 96/379 - (25%)

  Fly    15 KVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKH 75
            |||        |:|.||||.|||||.|.|  |:..|||:|    :..|:..:|.|||:||:||.|
  Rat     6 KVE--------KIGEGTYGVVYKAKNKLT--GEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60

  Fly    76 QNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIH 140
            .|::.|:.|.  |.:.|::|:.::...||   .||..|:..|.    :|..::||.|:|:|.|:.
  Rat    61 PNIVKLLDVI--HTENKLYLVFEFLHQDL---KKFMDASALTG----IPLPLIKSYLFQLLQGLA 116

  Fly   141 YLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELL 205
            :.||:.||||||||.|:|:    |..|.:|:||.|.||.|..|::....   .|||.||||||:|
  Rat   117 FCHSHRVLHRDLKPQNLLI----NAEGSIKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEIL 174

  Fly   206 LGARHYTKAIDIWAIGCIFAELLTSEPIFH--CRQEDIK-------------------------- 242
            ||.::|:.|:|||::||||||:       |  |.|...|
  Rat   175 LGCKYYSTAVDIWSLGCIFAEM-------HLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQ 232

  Fly   243 ------TSNPY------------HHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYS 289
                  .|.||            ..|||.|||..:|.|.:..|..:..||::......:.|..:|
  Rat   233 GGGMTAVSTPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS 297

  Fly   290 TCSLAKYMERHKIKP--DSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQP 341
                       |:.|  |.....||.::|..||||||:::.|:...:||:..:|
  Rat   298 -----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	125/367 (34%)
Cdk2	NP_001424913.1	None