DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk8 and Cdk7

DIOPT Version :9

Sequence 1:NP_536735.2 Gene:Cdk8 / 39157 FlyBaseID:FBgn0015618 Length:454 Species:Drosophila melanogaster
Sequence 2:NP_511044.1 Gene:Cdk7 / 31441 FlyBaseID:FBgn0263237 Length:353 Species:Drosophila melanogaster


Alignment Length:337 Identity:116/337 - (34%)
Similarity:179/337 - (53%) Gaps:53/337 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 VGRGTYGHVYKAKWKETSDGKEYALKQI-DGT------GLSMSACREIALLRELKHQNVITLIRV 84
            :|.|.:..||||  ::|...:..|:|:| .|:      |::.:|.|||.:|:||:|:|:|.|:.|
  Fly    18 LGEGQFATVYKA--RDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLVDV 80

  Fly    85 F--LSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWV 147
            |  ||:    |.|:.|:.:.||..|||        ..::::.:..:|:.....|.|:.|||.||:
  Fly    81 FGQLSN----VSLVFDFMDTDLEVIIK--------DNKIILTQANIKAYAIMTLKGLEYLHLNWI 133

  Fly   148 LHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYT 212
            |||||||.|:||    |..|.:||.|.|.|:.|.:|.:....   .|||.|||:||||.|||.|.
  Fly   134 LHRDLKPNNLLV----NSDGILKIGDFGLAKSFGSPNRIYTH---HVVTRWYRSPELLFGARQYG 191

  Fly   213 KAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHH 277
            ..:|:||:|||.|||:...| |.....|:        |||.|||:.:|.|.:.:|..:.|:.::.
  Fly   192 TGVDMWAVGCILAELMLRVP-FMPGDSDL--------DQLTRIFSTLGTPTEAEWPHLSKLHDYL 247

  Fly   278 TLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPT 342
            .. ::|..:.......|         ..:...||:|:|..|:|.:|::..:|:...||..:|.||
  Fly   248 QF-RNFPGTPLDNIFTA---------AGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPT 302

  Fly   343 QDVFAGCPIPYP 354
                .|..:|.|
  Fly   303 ----VGPKLPMP 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk8NP_536735.2 STKc_CDK8_like 19..335 CDD:270834 108/316 (34%)
S_TKc 22..335 CDD:214567 108/316 (34%)
Cdk7NP_511044.1 PTZ00024 6..308 CDD:240233 114/333 (34%)
STKc_CDK7 11..308 CDD:270833 114/333 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442383
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24056
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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