Protein Alignment Cdk8 and Cdk7

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 116/337 - (34%)
• Similarity: 179/337 - (53%)
• Gaps: 53/337 - (15%)

  Fly    27 VGRGTYGHVYKAKWKETSDGKEYALKQI-DGT------GLSMSACREIALLRELKHQNVITLIRV 84
            :|.|.:..||||  ::|...:..|:|:| .|:      |::.:|.|||.:|:||:|:|:|.|:.|
  Fly    18 LGEGQFATVYKA--RDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLVDV 80

  Fly    85 F--LSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWV 147
            |  ||:    |.|:.|:.:.||..|||        ..::::.:..:|:.....|.|:.|||.||:
  Fly    81 FGQLSN----VSLVFDFMDTDLEVIIK--------DNKIILTQANIKAYAIMTLKGLEYLHLNWI 133

  Fly   148 LHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYT 212
            |||||||.|:||    |..|.:||.|.|.|:.|.:|.:....   .|||.|||:||||.|||.|.
  Fly   134 LHRDLKPNNLLV----NSDGILKIGDFGLAKSFGSPNRIYTH---HVVTRWYRSPELLFGARQYG 191

  Fly   213 KAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHH 277
            ..:|:||:|||.|||:...| |.....|:        |||.|||:.:|.|.:.:|..:.|:.::.
  Fly   192 TGVDMWAVGCILAELMLRVP-FMPGDSDL--------DQLTRIFSTLGTPTEAEWPHLSKLHDYL 247

  Fly   278 TLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPT 342
            .. ::|..:.......|         ..:...||:|:|..|:|.:|::..:|:...||..:|.||
  Fly   248 QF-RNFPGTPLDNIFTA---------AGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPT 302

  Fly   343 QDVFAGCPIPYP 354
                .|..:|.|
  Fly   303 ----VGPKLPMP 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	108/316 (34%)
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	114/333 (34%)