Protein Alignment Cdk8 and srb10

DIOPT Version :9

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_593389.2
• Gene: srb10 / 2541900
• PomBaseID: SPAC23H4.17c
• Length: 369
• Species: Schizosaccharomyces pombe
• Alignment Length: 370
• Identity: 141/370 - (38%)
• Similarity: 215/370 - (58%)
• Gaps: 39/370 - (10%)

  Fly    27 VGRGTYGHVYKAKWKETSDGKEYALKQIDG-----------TGLSMSACREIALLRELKHQNVIT 80
            :..||||.||||....::|.:.:|:|:...           ||:|.||.||:.|.||::|:|:::
pombe    11 ISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQHENIVS 75

  Fly    81 LIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSN 145
            |::|.|  .|..:.::.:||||||..||.||..::..:    :|..::||:|:||::|:.|||.|
pombe    76 LVQVLL--KDGTISMVFEYAEHDLLQIIHFHSRSRTRQ----IPPSILKSILWQIINGVAYLHEN 134

  Fly   146 WVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARH 210
            |::|||||||||::    ...|:|||.|:|..||...|:.|....|.||||.|||||||||||..
pombe   135 WIMHRDLKPANIMI----TATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIWYRAPELLLGAHD 195

  Fly   211 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSN----PYHHDQLDRIFNVMGFPQDKDWEDIK 271
            ||.|||:||||||:.|:|...|:|  :.::||..:    |:...|:.||..::|.|.::.|..:|
pombe   196 YTPAIDVWAIGCIYGEMLALSPLF--KGDEIKMEDKKVVPFQSTQMLRIMELLGTPTEERWPGLK 258

  Fly   272 KMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQ 336
            ..||::.|:....|  |....|.::.:..|.: |.:...||.|:|..||..|||::||::..:|.
pombe   259 NYPEYYQLSSFEVR--YWNNLLPQWYQTVKNR-DPQGLDLLMKMLQYDPKSRITAKQALEHVFFT 320

  Fly   337 EEPQPTQDVFAGCPIPYPKREFLTDDDQED---------KSDNKR 372
            .:...|...|...||.||:|....||.:..         :|::||
pombe   321 SDKLWTTSPFLNQPIHYPERRISEDDSEVSSKRVLSTSLRSESKR 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	128/322 (40%)
		S_TKc	22..335	CDD:214567	128/322 (40%)
srb10	NP_593389.2	PTZ00024	1..324	CDD:240233	129/327 (39%)
		STKc_CDK8_like	4..319	CDD:270834	128/322 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	240	1.000	Domainoid score	I461
eggNOG	1	0.900	-	-		E1_KOG0666
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I765
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002084
OrthoInspector	1	1.000	-	-		oto100410
orthoMCL	1	0.900	-	-		OOG6_102974
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1399
SonicParanoid	1	1.000	-	-		X1379
TreeFam	0	0.000	Not matched by this tool.
	11	10.890