Protein Alignment Cdk8 and Cdk10

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_919428.1
• Gene: Cdk10 / 234854
• MGIID: 2448549
• Length: 360
• Species: Mus musculus
• Alignment Length: 327
• Identity: 114/327 - (34%)
• Similarity: 180/327 - (55%)
• Gaps: 48/327 - (14%)

  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86
            ::|.||||.||:|  ::|...:..|||::    :..|:.:|:.|||.||..|:|.|::.|..|.:
Mouse    44 RIGEGTYGIVYRA--RDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVV 106

  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVP--RGMVKSLLYQILDGIHYLHSNWVLH 149
            .::...:||::.|.|.||..::          :.:..|  ...||.::.|:|.|:.|||.|:::|
Mouse   107 GNHLESIFLVMGYCEQDLASLL----------ENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIH 161

  Fly   150 RDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKA 214
            ||||.:|:|:    .::|.||.||.|.||.:..|:||:.   |.|||.||||||||||....|.:
Mouse   162 RDLKVSNLLM----TDKGCVKTADFGLARAYGVPVKPMT---PKVVTLWYRAPELLLGTTTQTTS 219

  Fly   215 IDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMP--EHH 277
            ||:||:|||.||||..:|:       :..::..|  |:|.|..::|.|.:..|....|:|  ..:
Mouse   220 IDMWAVGCILAELLAHKPL-------LPGTSEIH--QIDLIVQLLGTPSENIWPGFSKLPLAGQY 275

  Fly   278 TLTKDFKRSTYSTCSLAKYMERHKIKPDSKA-FHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQP 341
            :|    ::..|:..       :||....|:| ..||..|.:.||.||.||...::..||:|:|.|
Mouse   276 SL----RKQPYNNL-------KHKFPWLSEAGLRLLNFLFMYDPKKRATSGDCLESSYFKEKPLP 329

  Fly   342 TQ 343
            .:
Mouse   330 CE 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	109/317 (34%)
Cdk10	NP_919428.1	STKc_CDK10	31..339	CDD:173742	114/327 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..360