Protein Alignment Cdk8 and cdk-5

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 123/342 - (35%)
• Similarity: 183/342 - (53%)
• Gaps: 65/342 - (19%)

  Fly    19 LFNYEGC-KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNV 78
            :.||:.. |:|.||||.|:||:.|  :.|:..|||::    |..|:..||.|||.:||||||:||
 Worm     1 MLNYDKMEKIGEGTYGTVFKARNK--NSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNV 63

  Fly    79 ITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLH 143
            :.|..|.  |::.|:.|:.:|.:.||   .||..:...     .:.....:||:.|:|.|:.:.|
 Worm    64 VRLYDVV--HSENKLTLVFEYCDQDL---KKFFDSLNG-----YMDAQTARSLMLQLLRGLSFCH 118

  Fly   144 SNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGA 208
            ::.||||||||.|:|:    |..|.:|:||.|.||.|..|::..:   ..|||.|||.|::|.||
 Worm   119 AHHVLHRDLKPQNLLI----NTNGTLKLADFGLARAFGVPVRCFS---AEVVTLWYRPPDVLFGA 176

  Fly   209 RHYTKAIDIWAIGCIFAELLTS-EPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKK 272
            :.|..:||:|:.||||||:..: .|:|.....|         |||.|||..:|.|.:.:|..|.:
 Worm   177 KLYNTSIDMWSAGCIFAEISNAGRPLFPGADVD---------DQLKRIFKQLGSPSEDNWPSITQ 232

  Fly   273 MPE-------HHTLTKDFKRSTYSTCSLAKYMERHKIKP--DSKAFHLLQKLLLMDPNKRITSEQ 328
            :|:       |.|||..                  :|.|  :|:...||||||:.:|..||.::.
 Worm   233 LPDYKPYPIYHPTLTWS------------------QIVPNLNSRGRDLLQKLLVCNPAGRIDADA 279

  Fly   329 AMQDQYFQEEPQPTQDV 345
            |::..||.:    |.||
 Worm   280 ALRHAYFAD----TSDV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	118/330 (36%)
cdk-5	NP_499783.1	STKc_CDK5	3..286	CDD:143344	118/328 (36%)