Protein Alignment Cdk8 and cdk-11.1

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_495617.1
• Gene: cdk-11.1 / 174244
• WormBaseID: WBGene00015203
• Length: 719
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 130/414 - (31%)
• Similarity: 213/414 - (51%)
• Gaps: 57/414 - (13%)

  Fly     6 KMKTQIERTKV--------EDLFNYEGC--KVGRGTYGHVYKAKWKETSDGKEYALKQI----DG 56
            |.||.|.:..|        .::..|| |  :|..||:|.||:.|.|.|.:  ..|||::    :.
 Worm   332 KQKTLIAQLPVFYPGLMGCRNIDEYE-CVNRVDEGTFGVVYRGKDKRTDE--IVALKRLKMEKEK 393

  Fly    57 TGLSMSACREI-ALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQ 120
            .|..::|.||| .||:...|.|::.:..:.|..|..|:::.:::.|||:..::  ...::..|:.
 Worm   394 EGFPITALREINMLLKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLL--DTMSRRNKRF 456

  Fly   121 VVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLK 185
            .:   |..|:||.|:|.||.::|..|:||||||.:|:|:    :.:|.:||||.|.||.:..|||
 Worm   457 SI---GEQKTLLQQLLSGIEHMHKLWILHRDLKTSNLLM----SHKGILKIADFGLAREYGDPLK 514

  Fly   186 PLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHD 250
            ....   :|||.|||:||||||.|.|:..:|:|::|||.||.:..:|:|..|.|         .:
 Worm   515 KFTS---IVVTLWYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGE---------LE 567

  Fly   251 QLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKL 315
            |:.:||..||.|.:..|..:.::.....||  |::..|:  .|.|.....::..|: .|.||..|
 Worm   568 QIKKIFMEMGTPTESIWPGVTELDGWKALT--FEKYPYN--QLRKRFLAGRLLNDT-GFKLLNGL 627

  Fly   316 LLMDPNKRITSEQAMQDQYFQEEPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQ 380
            |.:||..|.::.||:..::|.|||.|.           |..||.|...:.::  ||.....:|:|
 Worm   628 LTLDPKNRFSATQALDHEWFTEEPYPV-----------PPEEFPTFPAKSEQ--NKAPPPAKQKQ 679

  Fly   381 QQQQQQQQQQQQQQQQQQQQMNAE 404
            |:.:......:..:..:|.::..|
 Worm   680 QENRISHVDPETAKLLKQFEVRPE 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	109/322 (34%)
cdk-11.1	NP_495617.1	STKc_CDC2L1	350..647	CDD:173741	109/325 (34%)