Protein Alignment Cdk8 and cdk-2

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001021537.2
• Gene: cdk-2 / 171911
• WormBaseID: WBGene00019362
• Length: 338
• Species: Caenorhabditis elegans
• Alignment Length: 333
• Identity: 99/333 - (29%)
• Similarity: 178/333 - (53%)
• Gaps: 55/333 - (16%)

  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86
            ::|.||||.|:||  ....|..:.|||.|    |..|:..:..|||:.:::|:|.|::||..:..
 Worm    20 RIGEGTYGVVFKA--IHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDIIY 82

  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRD 151
            :::  |::::.::.:.||.::::......:     |:|...|||.::|:|..:.|.|...::|||
 Worm    83 ANS--KLYMVFEFIDRDLKNLLEMLEPTNS-----VLPPNYVKSFMWQLLSALSYCHLRRIVHRD 140

  Fly   152 LKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID 216
            |||.||||    ::.|.:||||.|.||.|:.|.:   :....|||.|||.||:|||::.|:.::|
 Worm   141 LKPQNILV----SDSGVIKIADFGLARNFSFPSR---NYTHEVVTLWYRPPEILLGSQRYSTSLD 198

  Fly   217 IWAIGCIFAELLTSEPIF--HCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTL 279
            :|::||||:|:.:::|:|  .|           ...||.:||.::|.|..|.|..:...|.:..:
 Worm   199 MWSLGCIFSEIASNKPLFPGEC-----------EISQLFKIFEIVGTPNIKSWPGVDSFPHYKAV 252

  Fly   280 ----TKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYF----- 335
                ..:.|:...::|.....::            :|:::|...|.:|:|::.|:..:||
 Worm   253 FPQWPVNLKKLEETSCLTGNGLD------------VLREILRYPPERRLTAKGALSHRYFLQNGF 305

  Fly   336 -QEEPQPT 342
             |..|..|
 Worm   306 TQNRPSVT 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	94/318 (30%)
cdk-2	NP_001021537.2	STKc_CDK_like	15..300	CDD:270823	94/318 (30%)