Protein Alignment Cdk8 and cdk-7

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001370652.1
• Gene: cdk-7 / 171784
• WormBaseID: WBGene00000408
• Length: 330
• Species: Caenorhabditis elegans
• Alignment Length: 359
• Identity: 123/359 - (34%)
• Similarity: 191/359 - (53%)
• Gaps: 61/359 - (16%)

  Fly    22 YEGCK-VGRGTYGHVYKAKWKETSDGKEYALKQID-GT------GLSMSACREIALLRELKHQNV 78
            |:..| :|.|.:.:||.|  ::...|:..|:|:|. |:      |::.:|.|||.||:|:.|.|:
 Worm     5 YDTIKHLGEGQFANVYLA--QDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNI 67

  Fly    79 ITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLH 143
            |.| |..:.|. ..:.|:.|:.:.||.|:||        .|::::....:|::..|:|.|:.:||
 Worm    68 IGL-RDVIGHR-TSIQLVFDFMDTDLEHVIK--------DKEIILMPAHIKNITMQMLLGLEFLH 122

  Fly   144 SNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGA 208
            .:|:|||||||.|:|:    |:.||||:.|.|.||.|.:|.:   :....|||.||||||||.||
 Worm   123 VHWILHRDLKPNNLLM----NKMGRVKLTDFGLARFFGSPNR---NYTHQVVTRWYRAPELLFGA 180

  Fly   209 RHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKM 273
            |.|...||||::|||.||||...|||. .:.||        |||.:|||::|.|..:.|.::.:|
 Worm   181 RSYGVGIDIWSVGCIIAELLLRNPIFP-GESDI--------DQLVKIFNILGCPTPETWPNMTEM 236

  Fly   274 PEHHTL---TKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYF 335
            ..:..:   |:....:.|.:.:....::            |:..:...||.||:|..|::|.:||
 Worm   237 NSYVIIKPQTEYMALNYYFSAAPQDLLD------------LMAGMWTFDPIKRLTCTQSLQMEYF 289

  Fly   336 QEEPQPTQDVFAGCPIPYP------KREFLTDDD 363
            :.:|....|.    .:|.|      ||....|||
 Worm   290 RTQPFCCLDE----ELPLPKKQQPQKRSRRLDDD 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	112/323 (35%)
cdk-7	NP_001370652.1	STKc_CDK7	4..302	CDD:270833	116/340 (34%)