Protein Alignment Cdk8 and Cdk8

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_319061.4
• Gene: Cdk8 / 1279351
• VectorBaseID: AGAMI1_000562
• Length: 515
• Species: Anopheles gambiae
• Alignment Length: 511
• Identity: 395/511 - (77%)
• Similarity: 418/511 - (81%)
• Gaps: 63/511 - (12%)

  Fly     1 MDYDFKMKTQIERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACR 65
            |||:||||||.||.||||||.|||||||||||||||||:.||.:|.|:||||||:||||||||||
Mosquito     7 MDYEFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKARRKEGNDAKDYALKQIEGTGLSMSACR 71

  Fly    66 EIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKS 130
            ||||||||||.|||.||||||||.||||:||.||||||||||||||||||||||.|:||:|||||
Mosquito    72 EIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKS 136

  Fly   131 LLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVV 195
            |||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||
Mosquito   137 LLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVV 201

  Fly   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   202 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMG 266

  Fly   261 FPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRIT 325
            ||||||||||:|||||||||||||||.|::|||.|||||||||||||||||||||||||||||||
Mosquito   267 FPQDKDWEDIRKMPEHHTLTKDFKRSNYASCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRIT 331

  Fly   326 SEQAMQDQYFQEEPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQQQQQQ 390
            |||||||.||.|:|.||.||||||||||||||||||:||:||.:.::||||||||||||||||||
Mosquito   332 SEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGEKRQQQQQQQQQQQQQQQQQQQ 396

  Fly   391 QQQQQQQQQQMNAEP-----------------------------------------------NAK 408
            ||||||||||...:.                                               |||
Mosquito   397 QQQQQQQQQQQQQQQQNNQQNQQGNQQQQQQNQQQSGNPMQQGGGAGGAGGGGQGGGGMDHNNAK 461

  Fly   409 RVRLSGAG----------NQQDFHHQQQQQQQQQQQQQQQQQQMMFN--QQQNFQR 452
            ||||:|..          .||::|    ||||||.||||||.|||||  ||..||:
Mosquito   462 RVRLAGPNGHPNNSQGGMTQQEYH----QQQQQQNQQQQQQNQMMFNSGQQGGFQQ 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	292/315 (93%)
Cdk8	XP_319061.4	None