Protein Alignment Cdk8 and Cdk11b

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_031687.2
• Gene: Cdk11b / 12537
• MGIID: 88353
• Length: 784
• Species: Mus musculus
• Alignment Length: 333
• Identity: 119/333 - (35%)
• Similarity: 188/333 - (56%)
• Gaps: 47/333 - (14%)

  Fly    23 EGC----------KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLREL 73
            :||          ::..||||.||:||.|:|.:  ..|||::    :..|..:::.|||..:.:.
Mouse   419 QGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDE--IVALKRLKMEKEKEGFPITSLREINTILKA 481

  Fly    74 KHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDG 138
            :|.|::|:..:.:..|..|::::::|.||||       ::...|.||..:| |.||:|:.|:|.|
Mouse   482 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDL-------KSLMETMKQPFLP-GEVKTLMIQLLSG 538

  Fly   139 IHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPE 203
            :.:||.||:||||||.:|:|:    :..|.:|:.|.|.||.:.:|||...   |||||.||||||
Mouse   539 VKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPLKAYT---PVVVTLWYRAPE 596

  Fly   204 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWE 268
            |||||:.|:.|:|:|::||||.||||.:|:|. .:.||        ||:::||..:|.|.:|.|.
Mouse   597 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP-GKSDI--------DQINKIFKDLGTPSEKIWP 652

  Fly   269 DIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQ 333
            ....:|.       .|:.|:|........:|.......:.|.|:.|.|...|.:||.:|..::.:
Mouse   653 GYNDLPA-------VKKMTFSEYPYNNLRKRFGALLSDQGFDLMNKFLTYYPGRRINAEDGLKHE 710

  Fly   334 YFQEEPQP 341
            ||:|.|.|
Mouse   711 YFRETPLP 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	114/325 (35%)
Cdk11b	NP_031687.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..401
		STKc_CDC2L1	421..712	CDD:173741	113/323 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	722..784