Protein Alignment Cdk8 and Cdk1

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_031685.2
• Gene: Cdk1 / 12534
• MGIID: 88351
• Length: 297
• Species: Mus musculus
• Alignment Length: 335
• Identity: 122/335 - (36%)
• Similarity: 188/335 - (56%)
• Gaps: 59/335 - (17%)

  Fly    16 VEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQ 76
            :||....|  |:|.||||.|||.:.:.|  |:..|:|:|    :..|:..:|.|||:||:||:|.
Mouse     1 MEDYIKIE--KIGEGTYGVVYKGRHRVT--GQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61

  Fly    77 NVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQV-VVPRG------MVKSLLYQ 134
            |:::|..|.:  .|.:::|:.::...||             ||.: .:|.|      :|||.|:|
Mouse    62 NIVSLQDVLM--QDSRLYLIFEFLSMDL-------------KKYLDSIPPGQFMDSSLVKSYLHQ 111

  Fly   135 ILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWY 199
            ||.||.:.||..||||||||.|:|:    :::|.:|:||.|.||.|..|::....   .|||.||
Mouse   112 ILQGIVFCHSRRVLHRDLKPQNLLI----DDKGTIKLADFGLARAFGIPIRVYTH---EVVTLWY 169

  Fly   200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQD 264
            |:||:|||:..|:..:|||:||.|||||.|.:|:||...|         .|||.|||..:|.|.:
Mouse   170 RSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSE---------IDQLFRIFRALGTPNN 225

  Fly   265 KDWEDIKKMPEHHTLTKDFKRS--TYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSE 327
            :.|.:::.:       :|:|.:  .:...|||.:::    ..|.....||.|:|:.||.|||:.:
Mouse   226 EVWPEVESL-------QDYKNTFPKWKPGSLASHVK----NLDENGLDLLSKMLVYDPAKRISGK 279

  Fly   328 QAMQDQYFQE 337
            .|::..||.:
Mouse   280 MALKHPYFDD 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	118/328 (36%)
Cdk1	NP_031685.2	STKc_CDK1_euk	3..287	CDD:270845	119/329 (36%)