Protein Alignment Cdk8 and cdk19

DIOPT Version :9

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001107512.1
• Gene: cdk19 / 100135368
• XenbaseID: XB-GENE-989176
• Length: 491
• Species: Xenopus tropicalis
• Alignment Length: 484
• Identity: 334/484 - (69%)
• Similarity: 375/484 - (77%)
• Gaps: 33/484 - (6%)

  Fly     1 MDYDFKMKTQIERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACR 65
            |||:||.|...||.|||:||.||||||||||||||||||.|:..|.||||||||:|||:||||||
 Frog     1 MDYEFKSKLSAEREKVEELFEYEGCKVGRGTYGHVYKAKRKDGKDEKEYALKQIEGTGISMSACR 65

  Fly    66 EIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKS 130
            ||||||||||.|||.|.:|||||:||||:||.||||||||||||||||:||.||.:.:||.||||
 Frog    66 EIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKS 130

  Fly   131 LLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVV 195
            |||||||||||||:|||||||||||||||||:|.|||||||||||||||||:|||||||||||||
 Frog   131 LLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVV 195

  Fly   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||:|||
 Frog   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMG 260

  Fly   261 FPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRIT 325
            ||.|||||||:||||:.||.|||:|:||:..||.||||:||:|||||.|.||||||.|||.||||
 Frog   261 FPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRIT 325

  Fly   326 SEQAMQDQYFQEEPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQQQQQQ 390
            |:||:||.||||:|.||.||||||.|||||||||.:|:.|:|::..:|.|.|.|||...|||...
 Frog   326 SDQALQDLYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKTEKNQQTQNQHQQQTATQQQTTV 390

  Fly   391 QQQQQQQQ---------------------QQMNAEPNAKRVRLSGAGNQ--------QDFHHQQQ 426
            ||||.|||                     ..:|..|..|:.|:..:.|.        .|:.|...
 Frog   391 QQQQVQQQNSSQTNGTGGTAGAALQHSQDSSLNQGPQNKKPRMGPSANNSGGPSLMPSDYQHSSS 455

  Fly   427 Q--QQQQQQQQQQQQQQMMFN--QQQNFQ 451
            :  .|...|...|.|..|.::  .||:.|
 Frog   456 RLGYQSNVQGSSQPQNAMGYSTTSQQSSQ 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	267/315 (85%)
		S_TKc	22..335	CDD:214567	265/312 (85%)
cdk19	NP_001107512.1	PKc_like	18..335	CDD:389743	267/316 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	564	1.000	Domainoid score	I233
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	670	1.000	Inparanoid score	I739
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287471at33208
OrthoFinder	1	1.000	-	-		FOG0002084
OrthoInspector	1	1.000	-	-		otm47443
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1379
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070