| Sequence 1: | NP_001097564.1 | Gene: | I-2 / 39156 | FlyBaseID: | FBgn0028429 | Length: | 310 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_080076.1 | Gene: | Ppp1r2 / 66849 | MGIID: | 1914099 | Length: | 206 | Species: | Mus musculus |
| Alignment Length: | 198 | Identity: | 73/198 - (36%) |
|---|---|---|---|
| Similarity: | 109/198 - (55%) | Gaps: | 35/198 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 115 PCKGILKTSRSFDKSGAS------------------FRKSAKFDELNVMQTFHPADKDYGHMKID 161
Fly 162 EPKTPYNYTEGFDEN-------RDELDTELLVEKLRIAANTQPSTESIEDDGSSGDDQPLSEEER 219
Fly 220 QRRREFERRRKAHYREFEAVKLARKLIQEEDDDDDDEDKGADSRPSG------SSQGASSSGRFA 278
Fly 279 SSS 281 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| I-2 | NP_001097564.1 | IPP-2 | 137..247 | CDD:282789 | 51/116 (44%) |
| Ppp1r2 | NP_080076.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..36 | 9/29 (31%) | |
| Required for binding PPP1CC | 12..17 | 4/4 (100%) | |||
| Required for binding the 'RVXF' binding groove of PPP1CC | 44..56 | 6/11 (55%) | |||
| IPP-2 | 46..165 | CDD:398578 | 52/118 (44%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 75..143 | 20/67 (30%) | |||
| Required for binding PPP1CC catalytic center, displacing metal ions and inhibition of PPP1CC catalytic activity | 148..151 | 2/2 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 164..206 | 10/40 (25%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 113 | 1.000 | Domainoid score | I6157 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4041 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 124 | 1.000 | Inparanoid score | I4702 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S2946 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1321970at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003529 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm8857 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_106897 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR12398 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4306 |
| SonicParanoid | 1 | 1.000 | - | - | X2894 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.810 | |||||