Protein Alignment CG43897 and SMPD1

DIOPT Version :9

• Sequence 1: NP_001261659.1
• Gene: CG43897 / 39153
• FlyBaseID: FBgn0264489
• Length: 1385
• Species: Drosophila melanogaster
• Sequence 2: NP_000534.3
• Gene: SMPD1 / 6609
• HGNCID: 11120
• Length: 631
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 56/257 - (21%)
• Similarity: 81/257 - (31%)
• Gaps: 97/257 - (37%)

  Fly   926 VTTPATESPPPSTPPPPPP--PPPRQLALQKPETEVTWERS---------------RSPSPLPSR 973
            ::.|....|||..|.||.|  |..|.|.|    |::.|:..               |..|.||..
Human   178 ISLPTVPKPPPKPPSPPAPGAPVSRILFL----TDLHWDHDYLEGTDPDCADPLCCRRGSGLPPA 238

  Fly   974 KYPA-------PLIEAPQRS--SSPYGLNPVQTKAPPSPVNLPAKFTHVPQLEGHNIGLLVKTAT 1029
            ..|.       ...:.|.|:  |...||.|.      .|.::......:|   .|::.      .
Human   239 SRPGAGYWGEYSKCDLPLRTLESLLSGLGPA------GPFDMVYWTGDIP---AHDVW------H 288

  Fly  1030 EPLQQSMSASSTMLAATPPRSAAQPTPFEFPSLEQAEEQHKFKSLASFDEVQRDFGVNRSFDNVS 1094
            :..|..:.|.:|:.|..  |....|.|. :|    |...|:...:.||
Human   289 QTRQDQLRALTTVTALV--RKFLGPVPV-YP----AVGNHESTPVNSF----------------- 329

  Fly  1095 PRPYLGIEG-------YKRVA-----WPPASEERIIREFTPQPQTQSPAPGAGGYYPQAHAP 1144
            |.|:  |||       |:.:|     |.||...|.:|              .||:|..:..|
Human   330 PPPF--IEGNHSSRWLYEAMAKAWEPWLPAEALRTLR--------------IGGFYALSPYP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43897	NP_001261659.1	DUF4749	7..108	CDD:292558
SMPD1	NP_000534.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		SapB	89..162	CDD:214797
		MPP_ASMase	203..498	CDD:277321	46/232 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900