DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43897 and smpdl3a

DIOPT Version :9

Sequence 1:	NP_001261659.1	Gene:	CG43897 / 39153	FlyBaseID:	FBgn0264489	Length:	1385	Species:	Drosophila melanogaster
Sequence 2:	XP_005170233.1	Gene:	smpdl3a / 541525	ZFINID:	ZDB-GENE-050327-61	Length:	444	Species:	Danio rerio

Alignment Length:	318	Identity:	66/318 - (20%)
Similarity:	105/318 - (33%)	Gaps:	84/318 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1078 DEVQRDFGVN----------RSFDNVSPRPYLGIEGYKRVAWP----PASE----ERIIREFTPQ 1124
            :|:..|..:|          :.|..:...|.||...|    ||    |.||    :.:.:.::|
Zfish   114 EELSTDVVINVIANMTRTIQQFFPQIPVYPALGNHDY----WPQDQFPTSENAIYDAVAKLWSP- 173

  Fly  1125 PQTQSPAPGA----GGYYPQAHAPTAAAAAPPQQQYGAP---SYDGQQPGAQWQQQQQQQQVPQQ 1182
              ..:||..|    ||:|.....|.....:.....|.:|   :.:...|..|:|..|:..::.:|
Zfish   174 --WLNPAAVATLQKGGFYSLVIKPGLRLLSLNTNLYYSPNEVTVNMSDPAGQFQWLQETLELSRQ 236

  Fly  1183 QYQP-QSQAQAP--YQP---------PQWNQP----------------------------QQQQQ 1207
            ..:. ...|..|  |.|         ..:|:.                            ..||.
Zfish   237 SMEKVYVIAHVPIGYLPFAKNTTAMRENYNEQLVKIFRNYSEVVEGQFYGHTHRDSIMVLLDQQG 301

  Fly  1208 QP--SYQASPYQQQQQQQPSYYPQQNGGSTYAQPPYNSYSQPQLPYSQDQTDLQQQQQQQQQQYP 1270
            :|  |...:|.....:.|...:....|...|...| :||:  .|...|...:|.:...:|:..:.
Zfish   302 KPVNSIFVTPAVTPIKSQIEPFSNNPGVRAYLYQP-DSYT--LLDIWQFYLNLTEANLEQRSGWK 363

  Fly  1271 GAYA-----GQDSYRGASPGIITLRKEAPVSQKPAPVYTSQPAAVSYQGGSKLRGDLK 1323
            ..|.     |.|..:..|...:.||.|.|.| |....|.|. ..|||...::..||.|
Zfish   364 LEYIMTEAFGIDDIQPGSLQELALRFEKPQS-KAFDKYFSN-FMVSYNISARCEGDCK 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43897	NP_001261659.1	DUF4749	7..108	CDD:292558
smpdl3a	XP_005170233.1	MPP_ASMase	36..330	CDD:277321	40/222 (18%)
smpdl3a	XP_005170233.1	Metallophos	71..291	CDD:278574	33/183 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900