DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilp3 and igf2b

DIOPT Version :9

Sequence 1:	NP_648360.2	Gene:	Ilp3 / 39151	FlyBaseID:	FBgn0044050	Length:	120	Species:	Drosophila melanogaster
Sequence 2:	NP_001001815.1	Gene:	igf2b / 324215	ZFINID:	ZDB-GENE-030131-2935	Length:	212	Species:	Danio rerio

Alignment Length:	103	Identity:	28/103 - (27%)
Similarity:	41/103 - (39%)	Gaps:	29/103 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LLLLILMIGGVQATMKLCGRKLPETLSKLCVYGFNAMTKRTLDPVNFNQIDGFEDRSL-LERLLS 80
            :|.|.|....|.:...|||.:|.:.|..:|                       |||.. ..|..|
Zfish    37 ILFLTLSAFEVASAETLCGGELVDALQFVC-----------------------EDRGFYFSRPTS 78

  Fly    81 DSSVQMLKTRRLRDGVFDECCLKSCTMDEVLRYCAAKP 118
            .|:.:..:.|    |:.:|||..||.:..:.:|| |||
Zfish    79 RSNSRRSQNR----GIVEECCFSSCNLALLEQYC-AKP 111

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilp3	NP_648360.2	IlGF_insulin_bombyxin_like	33..114	CDD:239832	19/81 (23%)
igf2b	NP_001001815.1	B domain	46..77		11/53 (21%)
		IlGF	49..115	CDD:239834	24/91 (26%)
		C domain	78..88		2/9 (22%)
		A domain	89..109		8/20 (40%)
		D domain	110..115		2/2 (100%)
		E domain	116..212
		IGF2_C	144..199	CDD:285554
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1644517at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010