Protein Alignment Zasp67 and LIMS3

DIOPT Version :10

• Sequence 1: NP_648358.2
• Gene: Zasp67 / 39148
• FlyBaseID: FBgn0036044
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_001381830.1
• Gene: LIMS3 / 96626
• HGNCID: 30047
• Length: 398
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 48/266 - (18%)
• Similarity: 70/266 - (26%)
• Gaps: 128/266 - (48%)

  Fly   496 IDENSGNEEQVEEGVTTATNTINTAGETEDAGKDISISGSDNPPVGPCESNEDRCDANDREVAEI 560
            |.||       ||....|.||::.|..|||                            :|.|:::
Human    12 IPEN-------EEIPRAALNTVHEANGTED----------------------------ERAVSKL 41

  Fly   561 SRSTDDNRLAKD----------------------------------KKKDLDQEQ----KQQQQQ 587
            .|...|.::.|:                                  ...:|..||    .|..||
Human    42 QRRHSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQ 106

  Fly   588 QQEPLSEEQNFKKQKRHD-------------------VIEELE---------------------- 611
            ..|.|..|...:|...||                   ||:.:.
Human   107 FPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 171

  Fly   612 -----EHLVRKNNPRRSKRAFGPLVPS------SERPLVLPGGRRWYRPKDAYNDEFIAETLSAQ 665
                 .||.|..:.|...|..|..:..      .|:||:.....  |.| |.:|.....:.|:|.
Human   172 VKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDP--YHP-DHFNCANCGKDLTAD 233

  Fly   666 AELITG 671
            |:.:.|
Human   234 AQELKG 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_ZASP52-like	4..84	CDD:467281
		DUF4749	653..>699	CDD:464948	5/19 (26%)
LIMS3	NP_001381830.1	LIM1_PINCH	72..130	CDD:188717	12/57 (21%)
		LIM2_PINCH	133..184	CDD:188718	5/50 (10%)
		LIM3_PINCH	197..247	CDD:188719	11/46 (24%)
		LIM4_PINCH	253..306	CDD:188720
		LIM5_PINCH	314..367	CDD:188721