DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp67 and pdlim3b

DIOPT Version :9

Sequence 1:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	XP_005157291.1	Gene:	pdlim3b / 561865	ZFINID:	ZDB-GENE-060130-104	Length:	332	Species:	Danio rerio

Alignment Length:	345	Identity:	74/345 - (21%)
Similarity:	117/345 - (33%)	Gaps:	106/345 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PWGFRLVGGADYDYPLTVVKVTEGSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGS---- 74
            ||||||.||.|::.|||:.:||.||.|....|...|||:.|...:...:||.||...|..|
Zfish    12 PWGFRLSGGKDFNQPLTITRVTPGSKASRVNLCPGDIILSIQGVSTDGMTHAEAQNNIKDSTNQL 76

  Fly    75 -------------------GSVFYFGVYRENEE---DAYECLKKFPTSEGSLTKSPMPTISPSPT 117
                               |.|..|.:..|.|:   |.:|  .||             .:.|.|.
Zfish    77 FLKIERPETKIWSPQVIEEGKVNPFKINLEAEKQDIDYFE--HKF-------------NVRPKPF 126

  Fly   118 PSLSQLTETTNARTPEPEPFVPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRGDVNG 182
            .|.||.:::|:      :..:....::|.....|.:|:.:..|.......:|....:.:...|..
Zfish   127 TSASQRSDSTS------QTLMGNVAQMAGTPSTAHSVQYNSPVALYSADNVSNTLQQAQMSTVVR 185

  Fly   183 HDAPGQADEGGLPVENLY--LPDLPDRPCSALSERQEIKLVEEEIAAVLSGESEVLKEHNVLGVN 245
            ..:|.......:...::|  |.|..::|   ...||             ||..:.|:::
Zfish   186 QASPSSKPLTSIEDSHVYRMLQDANEQP---HEPRQ-------------SGSFKALQDY------ 228

  Fly   246 FYRIFPKPGVCMSSD-----VLRSLNEEVTKTKLEKDKENRQWSTFLQRPNRPVPKSKQSLEAER 305
                       :.||     |.||:...|||.                   :....|.|.|....
Zfish   229 -----------VESDGTRPMVTRSVKAPVTKP-------------------QAATSSLQKLPLCD 263

  Fly   306 RAANAYKVTIVKSAPREKSP 325
            :.......|:||:..:.:.|
Zfish   264 KCGTGIVGTVVKARDKYRHP 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492	28/83 (34%)
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
pdlim3b	XP_005157291.1	PDZ_signaling	2..81	CDD:238492	28/68 (41%)
		DUF4749	156..232	CDD:292558	14/108 (13%)
		LIM_ALP	262..314	CDD:188834	4/22 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100