DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zasp67 and Tamalin

DIOPT Version :9

Sequence 1:NP_648358.2 Gene:Zasp67 / 39148 FlyBaseID:FBgn0036044 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_062391.3 Gene:Tamalin / 56149 MGIID:1860303 Length:392 Species:Mus musculus


Alignment Length:305 Identity:61/305 - (20%)
Similarity:85/305 - (27%) Gaps:101/305 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 DNVPWGFRLVGGADYDYPL------------TVVKVTEGSIADEAGLRVEDIIVRINDTAATPLT 63
            ||..:||.:     ..|.|            .|.:|.|.|.|..|||...|.|..:|......:.
Mouse   107 DNQTFGFEI-----QTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIR 166

  Fly    64 HDEAHRLIMGSGSVF----------------------------YFGVYR---------------- 84
            |.|...:|..||:|.                            .:|.||                
Mouse   167 HREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVK 231

  Fly    85 -----ENEEDAYECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTETTNART--------PEPEP 136
                 :..|....||.......|||...|:.....|......:....|:...        .||:.
Mouse   232 DPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAAPGSARGGARRAKGDTDDAVYHTCFFGGAEPQA 296

  Fly   137 FVPLP---RELAAATMAAPAVEVDVDVLAEC-RQPMSEVHSEEKRGDVNGHDAPG----QADEGG 193
            ..|.|   |.|..::...||     .||... |..:|...|....|...|..|||    :|.|..
Mouse   297 LPPPPPPARALGPSSAETPA-----SVLFPAPRSTLSRSASVRCAGPGGGGGAPGALWTEAREQA 356

  Fly   194 LPVENLYLPDLPDRPCSALSERQEIKLVEEEIAAVLSGESEVLKE 238
            |              |.|...:.:.:.....:...:.|.:..|:|
Mouse   357 L--------------CGAGLRKTKYRSFRRRLLKFIPGLNRSLEE 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp67NP_648358.2 PDZ_signaling 2..75 CDD:238492 20/75 (27%)
DUF4749 653..>699 CDD:292558
TamalinNP_062391.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50
PDZ_signaling 99..184 CDD:238492 23/81 (28%)
Interaction with PSCD3. /evidence=ECO:0000269|PubMed:10828067 180..257 9/76 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..315 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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