DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp67 and CG6688

DIOPT Version :9

Sequence 1:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_651110.1	Gene:	CG6688 / 42716	FlyBaseID:	FBgn0039038	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	92/457 - (20%)
Similarity:	154/457 - (33%)	Gaps:	162/457 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WGFRLVGGADYDYPLTVVKVTEGSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGSGSVFY 79
            :||:|.......|| .|.:|..|:.|...||:..|.::.:|......|...|..:::
  Fly    39 YGFQLTRSKWDPYP-WVCEVAAGTPAALCGLKPGDCVLEVNGNDVLGLRVSEIAKMV-------- 94

  Fly    80 FGVYRENEEDAY-------ECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTETTNARTPEPEPF 137
                 ::::|..       ||.|...|:  |:..:||||       ||.:|:....:..    ..
  Fly    95 -----KSQKDCVTILCWNSECDKDCDTN--SICCAPMPT-------SLRRLSLVLESIL----RL 141

  Fly   138 VPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRGDVNGHDAPGQADEGGLPVENLYLP 202
            |..|  :...|::.||:        :|:               |||               |...
  Fly   142 VECP--VCGVTISPPAM--------QCQ---------------NGH---------------LLCV 166

  Fly   203 DLPDRPCSALSERQEI---------KLVEEEIAAVLSGESEVLKEHNVLGVNFYRIFPKPGVCMS 258
            |     |...|||..:         .|:.|:|...::...|:.:..|.|....:....:|.|
  Fly   167 D-----CRIRSERCPVCRDFYTPRRALLAEQIFLTIANAFEMCRSENKLRQKLFAGITRPVV--- 223

  Fly   259 SDVLRSLNEEVTKTKLEKDKENRQWSTFLQRPNRPV-PKSK---QSLE---------AERRAANA 310
                              .:::|.......|..||| |.:|   :.||         :...||..
  Fly   224 ------------------GRQDRITGQDTWRKRRPVLPTNKFLTKLLEGCAYSTDNLSPSNAATL 270

  Fly   311 YKVTIVKSAPREKSPMPEAKPAPKEATPPKE------VEKKEEEP------VPEEVVEPEPEPEK 363
            .: |.......:.|.:| |:.:|..||||:.      ::.....|      :.:|.|:|..|...
  Fly   271 LR-TNTTDVAGDSSEIP-ARTSPVTATPPERTTMHATLDANAAHPSLSTNDLQQEGVKPNAEGVD 333

  Fly   364 DEE---------------PLPTDSEVPNLEQ---LPETELPDEQPEKSDAPKEVCEPEVVIQTEP 410
            :|.               |||. |..|.:.:   |....:|...|.: |.|::      |:||:|
  Fly   334 EESGTNSSHISATSLHGPPLPA-SVSPGINESSGLQPVRIPPVTPSQ-DLPQQ------VVQTKP 390

  Fly   411 GS 412
            .|
  Fly   391 AS 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492	15/59 (25%)
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
CG6688	NP_651110.1	PDZ_signaling	24..104	CDD:238492	16/78 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900