DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zasp67 and Syn1

DIOPT Version :9

Sequence 1:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster

Alignment Length:	244	Identity:	62/244 - (25%)
Similarity:	85/244 - (34%)	Gaps:	55/244 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IKMCRFDNVPWGFRLVGGADYDYPLTVVKVTEGSIADEA-GLRVEDIIVRINDTAATPLTHDEAH 68
            :::.:.||...|..:.||.:...|:.:.|:..|..||:| ||.|.|.|:.:|.......|||||.
  Fly   165 VRIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAV 229

  Fly    69 RLIMGSGSVF------------YFGVYRENEEDAYECLKKF--PTSEGSLTKSPMPTISPSPTPS 119
            |.:..||.|.            ||.......|..:|..:.|  |...|..|..|.|..:|.....
  Fly   230 RALKRSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTR 294

  Fly   120 LSQLTETTNART-----PEPEPFVPLPREL-------AAATMAAPAVEVDV-------------- 158
            ...|..|..||.     ||...|     ||       :....||.:.|..|
  Fly   295 YIPLQLTHLARNLKYIDPENRCF-----ELHSPDGVHSCILRAADSAEALVWFNALHSAMGTSTQ 354

  Fly   159 DVLAECRQPMSEVHSEEKR---------GDVNGHDAPGQADEGGLPVEN 198
            ..|||..:.::.:..|.|.         |..:...|.|.|..||....|
  Fly   355 RALAEANRALTNLIGELKHIGWLSKRMSGGGSSGSAGGGAASGGSGTSN 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492	23/70 (33%)
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	26/78 (33%)
		PHsplit_syntrophin	<293..351	CDD:269960	13/62 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900