DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zasp67 and ssp6

DIOPT Version :9

Sequence 1:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster

Alignment Length:	619	Identity:	116/619 - (18%)
Similarity:	187/619 - (30%)	Gaps:	195/619 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 PSPTPSLSQLTETTNARTPEPEPFVPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRG 178
            |..|...|..|..::|.|          ...|.:..|:.|..|...:.|.|:|.....|....:.
  Fly     5 PMSTSCQSIATAASSAAT----------TAAAVSISASNATSVGSLIAAACQQEQPHPHQHYSQS 59

  Fly   179 D---------------VNG---------HDAPGQADEG-------------GLPVENLYLPDLPD 206
            .               |||         |.:...:||.             |......||...||
  Fly    60 QQQHLYHQSHQQASHYVNGTGSLGRLKFHKSLDASDEEIEYAQLSRSTHILGRHKSERYLASNPD 124

  Fly   207 RPCSALSERQEIKLVEEE------------IAAVLSGESEVLK--EHNVLGVNFYRIFPKPGVCM 257
            .     ..|:...:||::            |......|.|::.  ::...|...||...:.|
  Fly   125 E-----DRRRRTIIVEKKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAGMREG--- 181

  Fly   258 SSDVLRSLN-------EEVTKTKLEKDKENR---------------------QWSTFLQRP---- 290
              ||:.|:|       :..|..:..|..:.|                     |..:.||:.
  Fly   182 --DVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMNEL 244

  Fly   291 NRPVPKSKQSLEAERRAANAYKVTIVKSAPREKSPMPEAKPAPKEATPPKEVEKK--------EE 347
            .|...:.::.||.:.:         ..|.|..|.......|:..|...|.||..:        ..
  Fly   245 ERVHLRERELLEGKWK---------THSLPARKKANANTSPSDGEGVSPTEVAGEAGFYRPALST 300

  Fly   348 EPVPE-----------EVVEP-----------EPEPEKDEEPLPTDSE--VPNL--------EQL 380
            |.||.           .::.|           :|.......|....||  |..|        .|.
  Fly   301 EDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTHGSSEEFVDGLGLQRSSSDHQP 365

  Fly   381 PETELPDEQPEKSDAPKEVCEPEVVIQTEPGSPDGNEAS-DGPAGAT-----PPAEPITPVPVKS 439
            |......:|.|..|| ..:.:|.....|:..|..|.... ..|...|     |||:|..|...||
  Fly   366 PAQRYVLQQTESVDA-NSMTQPTTTAPTQYHSTTGGSVKPPAPPPRTCEKHKPPAKPPKPEKEKS 429

  Fly   440 EEE-----LALERQLADVQRQLAALSSLPSTIQSTLDA--VTKQLAD--LLPTIKLQQQEKQLPQ 495
            ..:     .:....|...:.:.|..|::|:....:|||  :.....|  .:|:.:..:|.|:...
  Fly   430 SGKHCHVGHSCNPCLGHFRWKSAEKSAVPAPDNVSLDAYDLASPCCDTHCVPSRRRHRQHKEHTH 494

  Fly   496 IDENSGNE--EQVEEGVTTATNTINTAGETEDAGKDISISGSDNPPVGPCESNEDRCDANDREVA 558
            ..::...|  |..|:.|...:.:..:......||     ||..:.......|:|.:
  Fly   495 KHKHRDRERVESKEQRVRPKSTSHASPNANGGAG-----SGHHHHHHHHHHSHEQQ--------- 545

  Fly   559 EISRSTDDNRLAKDKKKDLDQEQKQQQQQQQEPL 592
                       .:.:::...|:|:|||||||:|:
  Fly   546 -----------QQQQQQQQQQQQQQQQQQQQQPI 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	16/90 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900