DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp67 and Prickle4

DIOPT Version :9

Sequence 1:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_001277266.1	Gene:	Prickle4 / 381104	MGIID:	2685785	Length:	369	Species:	Mus musculus

Alignment Length:	142	Identity:	35/142 - (24%)
Similarity:	51/142 - (35%)	Gaps:	48/142 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 EPEPEKDEEPLPTDSEVPNLEQLPETELPDEQPEKSDAPKEVCEPEVVIQTEPGSP--DGNEASD 420
            ||:|     |:.|||:        ....|.|..|.:.|....|       :..|.|  |.|:.|:
Mouse    19 EPDP-----PVYTDSD--------SGRRPVEDYEDTSAQAATC-------SSLGPPCLDINQVSN 63

  Fly   421 GPAGAT-----PPAEPITPVPVKSEEELAL---ERQLADV-----QRQLAALSS-----LPSTIQ 467
            .|...|     ||.:        |:|...|   |.:||.:     ||:..:|..     ||..::
Mouse    64 WPGFRTLLQQLPPQD--------SDERYCLALGEEELAQLRLFCAQRKQKSLGQGVARLLPPKLE 120

  Fly   468 STLDAVTKQLAD 479
            .......|:|.|
Mouse   121 GYTCKKCKKLLD 132

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
Prickle4	NP_001277266.1	PET_OEBT	1..116	CDD:193603	30/124 (24%)
		LIM1_Testin_like	124..181	CDD:188726	3/9 (33%)
		LIM2_Testin_like	187..241	CDD:188727
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100