DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp67 and Lnx1

DIOPT Version :9

Sequence 1:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_001101828.1	Gene:	Lnx1 / 360926	RGDID:	1308159	Length:	728	Species:	Rattus norvegicus

Alignment Length:	406	Identity:	85/406 - (20%)
Similarity:	138/406 - (33%)	Gaps:	133/406 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VLDIKMCRFD-NVPWGFRLVGGADYDYPLTVVKV----TEGSIADEAGLRVEDIIVRINDTAATP 61
            :..||:.|.| |.....|||||:  :.||..:.:    .:|.||.:..|...|||:::|....:.
  Rat   276 ITSIKINRVDPNESLSIRLVGGS--ETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISN 338

  Fly    62 LTHDEAHRLIMGSGSVFYFGVYRENEEDAYECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTET 126
            :.|:.|.||:.....|....|.||         :||    .|.:.:|.|   .|..|........
  Rat   339 VPHNYAVRLLRQPCQVLRLTVLRE---------QKF----RSRSNAPAP---DSYGPRDDSFHVI 387

  Fly   127 TNARTPEPEPFVPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRGD----VNGHD--- 184
            .|..:||.:..:.|.|.:.         |..|.:.......:::.|.:.:..|    :||||
  Rat   388 LNKSSPEEQLGIKLVRRVD---------EPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRF 443

  Fly   185 -APG------QADEG--GLPVENLYLPDLPD--RPCSALSERQEIKL-------------VEEEI 225
             :|.      ||.|.  .|.|........||  :....:|..|:..:             ..|::
  Rat   444 GSPESAAHLIQASERRVHLVVSRQVRQPSPDIFQEAGCISNGQQSPVSGERSTSSKPAATCHEKV 508

  Fly   226 AAVLSGESEVL-------KEHNVLGVNFYRIFPKPGVCMS-------SDVLRSLN----EEVTKT 272
            .:|....:|.|       ..|....:..|.|..:||..:|       .|:|.::|    .||::|
  Rat   509 VSVQKDPNESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRT 573

  Fly   273 KLEKDKENRQWSTFLQRPNRPVPKSKQSLEAERRAANAYKVTIVKSAP----------REKSPMP 327
            :                                      .|.|:||.|          :|:....
  Rat   574 E--------------------------------------AVAILKSTPSSVVLKALEVKEQETQE 600

  Fly   328 EAKPAPKEA----TPP 339
            :..||..::    |||
  Rat   601 DCSPAALDSNHNVTPP 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492	24/77 (31%)
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
Lnx1	NP_001101828.1	RING	45..81	CDD:214546
		DegQ	<260..364	CDD:223343	28/98 (29%)
		PDZ_signaling	276..360	CDD:238492	25/85 (29%)
		PDZ_signaling	384..464	CDD:238492	18/88 (20%)
		PDZ_signaling	506..589	CDD:238492	21/120 (18%)
		PDZ_signaling	637..721	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900