DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zasp67 and Pdlim2

DIOPT Version :9

Sequence 1:NP_648358.2 Gene:Zasp67 / 39148 FlyBaseID:FBgn0036044 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_001007623.1 Gene:Pdlim2 / 290354 RGDID:1359203 Length:349 Species:Rattus norvegicus


Alignment Length:372 Identity:85/372 - (22%)
Similarity:118/372 - (31%) Gaps:149/372 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 PWGFRLVGGADYDYPLTVVKVTEGSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGSGSVF 78
            |||||:.||.|:..|:.|.||||...|:.|.||..||||.||..:|..:.|.||...|..|.|  
  Rat    12 PWGFRISGGRDFHTPIIVTKVTERGKAEAADLRPGDIIVAINGESAESMLHAEAQSKIRQSAS-- 74

  Fly    79 YFGVYRENEEDAYECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTETTNARTPEPEPFVPLPRE 143
                                                                        ||..:
  Rat    75 ------------------------------------------------------------PLRLQ 79

  Fly   144 LAAATMAAPAV---EVDVDVLAECRQPMSEVHSEEKRGDVNGHDAPGQADEGGLPVENLYLPDLP 205
            |..:..|:|..   |..:|:||...|.....|...:....:...:|..            |...|
  Rat    80 LDRSQTASPGQINGEGSLDMLATRFQGSLRTHHNSQSSQRSACFSPAS------------LSPRP 132

  Fly   206 DRPCSALSERQEIKLVEEEIAAVLSGESEVLKEHNVLGVNFYRIFPKPGVCM------------- 257
            |.|.|.......|         .||||       ||:|.:|..:...||:..             
  Rat   133 DSPFSTPPPTSPI---------ALSGE-------NVIGCSFQSLTHSPGLAATHHLTYPGQPTSQ 181

  Fly   258 -------SSDVLRSL--------NEEVTKTKLEKD-------KENRQWSTFLQRPNRPVPKS--- 297
                   |...:|.|        :..::...||:|       :||||        .|..|:.   
  Rat   182 QAGHSSPSDSTVRVLLHSPGRPSSPRLSSLDLEEDSEVFKMLQENRQ--------GRAAPRQSSS 238

  Fly   298 ----KQSLEAERRAANAYKVTIVKSAPREKSPMPEAKPAPKEATPPK 340
                :::||||.|....   ..|.|:...|:.:|.::..   |||||
  Rat   239 FRLLQEALEAEERGGTP---AFVPSSLSPKASLPTSRAL---ATPPK 279

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp67NP_648358.2 PDZ_signaling 2..75 CDD:238492 29/60 (48%)
DUF4749 653..>699 CDD:292558
Pdlim2NP_001007623.1 PDZ_signaling 9..80 CDD:238492 33/129 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..95 7/84 (8%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 108..147 8/59 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 168..212 3/43 (7%)
DUF4749 <190..252 CDD:292558 15/69 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 250..272 5/24 (21%)
LIM_Mystique 283..335 CDD:188833
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 59 1.000 Domainoid score I10444
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24214
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.100

Return to query results.
Submit another query.