DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp67 and Pdzd3

DIOPT Version :9

Sequence 1:NP_648358.2 Gene:Zasp67 / 39148 FlyBaseID:FBgn0036044 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_573489.2 Gene:Pdzd3 / 170761 MGIID:2429554 Length:498 Species:Mus musculus


Alignment Length:499 Identity:98/499 - (19%)
Similarity:160/499 - (32%) Gaps:172/499 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 WGFRL---VGGADYDYPLTVVKVTEGSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGSGS 76
            :||.|   :|.||:    .|.:|..|:.|...|||..|.|:.:|:.......|....|.|..||.
Mouse    60 FGFHLQQHLGKADH----VVCRVDPGTSAQRQGLREGDRILAVNNNIVAHEDHAVVVRYIRASGP 120

  Fly    77 VFYFGVYRENEEDAYECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTE---------TTNARTP 132
            .....|..::..|....|:   .|:..|    .||:.....|.|..:.:         |..:|.|
Mouse   121 RVLLTVLAQHVHDVARVLQ---GSDAFL----CPTLPSGVRPRLCHVVKDEGGFGFSVTHGSRGP 178

  Fly   133 EPEPFVPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEK---RGD-----VNGHDAPGQA 189
            .   ::.|....||.....|.....::|.....:.::......|   .||     |.|.:...|.
Mouse   179 F---WLVLSAGGAAERAGVPPGARLLEVNGASVEKLTYNQLNRKLWQSGDQVTLLVAGLEVEEQC 240

  Fly   190 DEGGLPV-----ENLYLPDLPDRPCSALSERQEIKLVEEEIAAVLSGESEVLKEH----NVLGVN 245
            .:.|:|:     |...||..|  .|..:.:..|             |...:|:|.    ..||..
Mouse   241 HQLGMPLAAPLAEGWALPAKP--RCLNIEKGPE-------------GFGFLLREEKGLDGRLGQF 290

  Fly   246 FYRIFP---------KPG---VCMSSDVLRSLNEEVTKTKLEKDKENRQWSTFLQRPNRPVPKSK 298
            .:.:.|         |.|   |.::.:.:..|..|.|.:::.  .:....|..:..|        
Mouse   291 LWDVDPGLPADKAGMKAGDRLVAVAGESVDGLGHEETVSRIR--AQGSCVSLIVVDP-------- 345

  Fly   299 QSLEAERRAANAYKVTIVKSAP---REKSPMPEAKPAPKEATPPKEVEKKEEEPVPEEVVEPE-- 358
               ||:|      ..::|:.:|   .|.:.:         |.||  :.:.::.|| |:.|||.  
Mouse   346 ---EADR------FFSMVRLSPLLFLENTEI---------AAPP--LAETKDLPV-EDTVEPSGL 389

  Fly   359 ---------PEP----------------------------------------EKDEEPLPTDSEV 374
                     |.|                                        |.:..|:..|||:
Mouse   390 AGSCQCFLYPGPGGGYGFRLCCVASGPCLFISQVTPGGSAARAGLQVGDTVLEVNGYPVGGDSEL 454

  Fly   375 PNLEQLPETELPDEQPEKSDAPKEVCEPEVVIQTEPGSPDGNEA 418
            ..|:||.|                 .||.:.::....:|.|.||
Mouse   455 DRLQQLTE-----------------AEPPLCLKLGARNPQGLEA 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp67NP_648358.2 PDZ_signaling 2..75 CDD:238492 19/62 (31%)
DUF4749 653..>699 CDD:292558
Pdzd3NP_573489.2 PDZ_signaling 47..127 CDD:238492 21/70 (30%)
PDZ_signaling 155..232 CDD:238492 13/79 (16%)
PDZ 260..345 CDD:214570 16/101 (16%)
PDZ_signaling 407..471 CDD:238492 11/80 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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