DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp67 and Lnx1

DIOPT Version :9

Sequence 1:NP_648358.2 Gene:Zasp67 / 39148 FlyBaseID:FBgn0036044 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_001153049.1 Gene:Lnx1 / 16924 MGIID:1278335 Length:728 Species:Mus musculus


Alignment Length:425 Identity:88/425 - (20%)
Similarity:135/425 - (31%) Gaps:171/425 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 VLDIKMCRFD-NVPWGFRLVGGADYDYPLTVVKV----TEGSIADEAGLRVEDIIVRINDTAATP 61
            :..||:.|.| :.....|||||:  :.||..:.:    .:|.||.:..|...|||:::|....:.
Mouse   276 ITSIKINRADPSESLSIRLVGGS--ETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISN 338

  Fly    62 LTHDEAHRLIMGSGSVFYFGVYRENEEDAYECLKKF--------PTSEGS--------LTKSPMP 110
            :.|:.|.||:.....|....|.||         :||        |.|.|.        |.||   
Mouse   339 VPHNYAVRLLRQPCQVLRLTVLRE---------QKFRSRSNAHVPDSYGPRDDSFHVILNKS--- 391

  Fly   111 TISPSPTPSLSQLTETTNARTPEPEPFV---------------------------------PLPR 142
              ||.     .||......|..||..|:                                 |   
Mouse   392 --SPE-----EQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSP--- 446

  Fly   143 ELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRGDV-NGHDAPGQADEGGLPVENLYLPDLPD 206
            |.||..:.|....|.:.|..:.||...::..|  .|.: ||..:||..:.           :...
Mouse   447 ESAAHLIQASERRVHLVVSRQVRQSSPDIFQE--AGWISNGQQSPGPGER-----------NTAS 498

  Fly   207 RPCSALSERQEIKLVEEEIAAVLSGESEVL-------KEHNVLGVNFYRIFPKPGVCMS------ 258
            :|.:.         ..|::.:|....||.|       ..|....:..|.|..:||..:|      
Mouse   499 KPAAT---------CHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIK 554

  Fly   259 -SDVLRSLN----EEVTKTKLEKDKENRQWSTFLQRPNRPVPKSKQSLEAERRAANAYKVTIVKS 318
             .|:|.::|    .||::|:                                      .|.|:||
Mouse   555 TGDILLNVNGIELTEVSRTE--------------------------------------AVAILKS 581

  Fly   319 AP----------REKSPMPEAKPAPKEA----TPP 339
            ||          :|:....:..||..::    |||
Mouse   582 APSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPP 616

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp67NP_648358.2 PDZ_signaling 2..75 CDD:238492 23/77 (30%)
DUF4749 653..>699 CDD:292558
Lnx1NP_001153049.1 mRING-HC-C3HC3D_LNX1 42..83 CDD:319693
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..220
NPXY motif 185..188
Interaction with MAGEB18. /evidence=ECO:0000250 186..244
PDZ_signaling 276..360 CDD:238492 24/85 (28%)
PDZ_signaling 384..464 CDD:238492 17/92 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 481..500 4/29 (14%)
PDZ_signaling 506..589 CDD:238492 23/120 (19%)
PDZ_signaling 637..721 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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