DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp67 and Lnx2

DIOPT Version :9

Sequence 1:NP_648358.2 Gene:Zasp67 / 39148 FlyBaseID:FBgn0036044 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_542985.4 Gene:Lnx2 / 140887 MGIID:2155959 Length:687 Species:Mus musculus


Alignment Length:515 Identity:90/515 - (17%)
Similarity:152/515 - (29%) Gaps:211/515 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 GFRLVGGADYDYPLTVVKVTE----GSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGSGS 76
            |..:|||  .:.||..:.:.|    |.||.:..|...|.|:::|:...:.::|:.|..::....|
Mouse   245 GISIVGG--NETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYDISNVSHNHARAVLSQPCS 307

  Fly    77 VFYFGVYRENEEDAYECLKKFPT-----SEGSLTKSPMPTISPSPTPSLSQLTETTNARTPEPEP 136
            .....|.||         ::|.:     ::||..:..:..:......|..||......||.||..
Mouse   308 TLQLTVLRE---------RRFGSRANSHADGSAPRDEVFQVLLHKRDSTEQLGIKLVRRTDEPGV 363

  Fly   137 FVPLPRELAAATMAAPAVEVDVDVLAECRQPMSEVHSEEKRGDVNGHDAPGQADEGGLPVENLYL 201
            |:   .:|....:||..               ..::|.::...:||||.     :.|.|      
Mouse   364 FI---LDLLEGGLAAQD---------------GRLNSNDRVLAINGHDL-----KHGTP------ 399

  Fly   202 PDLPDRPCSALSERQEIKLVEEEIAAVLSGESEVLKEHNVLGVNFYRIFPKPGVCMSSDVLRSLN 266
                                  |:||                                .::::..
Mouse   400 ----------------------ELAA--------------------------------QIIQASG 410

  Fly   267 EEVTKTKLEKDKENRQWSTFLQRPNRPVPKSKQSLEAERRAANAYKVTIVKSAPREKSPMPEAKP 331
            |.|..|              :.||.:|.|.:..      |.|.|:      |:.....|...::|
Mouse   411 ERVNLT--------------IARPGKPQPSNGS------REAGAH------SSSNHAQPPSHSRP 449

  Fly   332 -APKEATPPKEVEKKEEEPVPEEVVEPEPEPEKDEEPLPTDSEVPNLEQLPETELPDEQPEKSDA 395
             :.|:.|.....::|      ...|:.||.                 |.|..|.......:..:.
Mouse   450 GSHKDLTRCVTCQEK------HITVKKEPH-----------------ESLGMTVAGGRGSKSGEL 491

  Fly   396 PKEVCEPEVVIQTEPGSPDGNEASDG----------------------------PAGATPPAEPI 432
            |       :.:.:.|  |.|..|.||                            .|.|..||..:
Mouse   492 P-------IFVTSVP--PHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVIL 547

  Fly   433 TPVPVKSEEELALERQLADVQRQLAALS----------------SLPSTIQSTLDAVTKQ 476
            ..:.|:..||.|     ...:.|.:|.|                .|||.:.|..|.|.::
Mouse   548 KALEVQIAEEAA-----QATEEQPSAFSENEYDASWSPSWVMWLGLPSALHSCHDIVLRR 602

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp67NP_648358.2 PDZ_signaling 2..75 CDD:238492 16/62 (26%)
DUF4749 653..>699 CDD:292558
Lnx2NP_542985.4 mRING-HC-C3HC3D_LNX2 46..90 CDD:319694
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 145..175
NPXY motif 207..210
PDZ 229..315 CDD:214570 18/71 (25%)
PDZ_signaling 336..418 CDD:238492 24/178 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 417..454 10/48 (21%)
PDZ_signaling 463..539 CDD:238492 14/107 (13%)
PDZ_signaling 596..680 CDD:238492 2/7 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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