DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ae2 and AT5G25430

DIOPT Version :9

Sequence 1:	NP_648357.1	Gene:	Ae2 / 39147	FlyBaseID:	FBgn0036043	Length:	1268	Species:	Drosophila melanogaster
Sequence 2:	NP_001318647.1	Gene:	AT5G25430 / 832617	AraportID:	AT5G25430	Length:	671	Species:	Arabidopsis thaliana

Alignment Length:	641	Identity:	147/641 - (22%)
Similarity:	258/641 - (40%)	Gaps:	145/641 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   707 GLRNDLKRRMPMYKSDILDGLNT--ETLAATIFMYFACLSTAITFGGLVSAKTNSWIGISETLIS 769
            |:..|::.|...||.|.:.|:.|  ..||.|.:::||.....:.||..:|..|...:...|||.|
plant    12 GILRDIEGRRKCYKQDWIRGIKTGIRILAPTCYIFFASSLPVVAFGEQLSKHTGGALSAVETLAS 76

  Fly   770 CSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFD-----FLSLRVYVGVWLIIIALT 829
            .|:.||:......|||:|:|...|.::....|..||.... |     :|:...:|.||..::.:.
plant    77 TSICGIIHAIFGGQPLLIVGVAEPTIIMYTYLYSFCISRP-DIGRELYLAWVAWVCVWTSVLLIL 140

  Fly   830 VSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPPPTLVAHEHATN 894
            :|.|.....:...||...|:|..||.::::.|....|||.:.           .|.:...|...:
plant   141 LSIFNAGTIITRFTRIAGELFGMLIAVLFLQEAIKGLISEFH-----------APEIKNQETGKS 194

  Fly   895 ESLLNATASVTTNITQMVMNISTTAMPIGPPPLPKNQPNTALFCTILTLATFVVAYYLKLFRNSH 959
            ..||     :..|                           .|...|.:|...:.|...:..::..
plant   195 HFLL-----IYAN---------------------------GLLAVIFSLGLLITALKSRRAKSWK 227

  Fly   960 FLGRNARRALGDFGVPISIAIFVLVDYLVPAVYTEKLVVPEGL---SPSDP-SKRGWYIGFDTSS 1020
            :.....|..:||:|||:.:.::..:.|.||:.....  ||..|   .|.:| |...|.:..|...
plant   228 YGFGWLRSFIGDYGVPLMVLLWTALSYTVPSEVLPS--VPRRLFCPLPWEPASLYHWTVVKDMGK 290

  Fly  1021 TWIPF--ACVIPALLVYILIFMESQISELIVDKPDRGLKKGSGLHWDIVLLCLLNCACGIFGMPW 1083
            ..|.:  |..||.:::..|.|.:..::..:..:.:..||..|..|:||.||.::...||:.|:|.
plant   291 VPIMYILAAFIPGVMIAGLYFFDHSVASQMAQQKEFNLKNPSAYHYDIFLLGIITLICGLLGLPP 355

  Fly  1084 HCAATVRSVTHVSSVTIMSR------------------------------------THAPGESPR 1112
            ......::..|..|:.:::|                                    |..|.::..
plant   356 SNGVLPQAPMHTKSLAVLNRQLIRKKMVKKAKECMKMKASKSEIYGRMQSVFIEMETSPPQDNSV 420

  Fly  1113 IVDVK----------------------------------EQRLSGFFVCLMIGLSVLMAPLLRLI 1143
            ..|:|                                  |||:|.....:::||::|...::::|
plant   421 ATDLKELKEVVMRPDEGGDTKGKFDPDVHIEANLPVRVNEQRVSNLLQSVLVGLTLLAVTVIKMI 485

  Fly  1144 PMAVLFGVFLYMGVASMSGVQLFERIRLYFMP------VKHYPPTSYVKRLRPWKLHL-FTTIQ- 1200
            |.:||:|.|.||.:.|:.|.|.:||:.|.|:|      |......|:|: |.|:::.: ||..|
plant   486 PSSVLWGYFAYMAIDSLPGNQFWERLLLLFIPPSRLFKVLEGVHASFVE-LVPYRVIVTFTLFQL 549

  Fly  1201 ---VLCLVLLWSVKSSQFSLAFPFFLIMMVPIRQN-LTKLYKPEEMQALDGSEMKK 1252
               :||..:.|...:..|   ||....:::.||:: |.||:..:.:|.||.|:.::
plant   550 VYFLLCYGMTWIPMAGIF---FPALFFLLISIREHLLPKLFDMQHLQVLDASDYEE 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ae2	NP_648357.1	ae	260..1267	CDD:273290	147/641 (23%)
		Band_3_cyto	287..618	CDD:284893
		HCO3_cotransp	698..1199	CDD:279322	131/581 (23%)
AT5G25430	NP_001318647.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1172
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265068at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1016
orthoMCL	1	0.900	-	-		OOG6_100185
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X102
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720