Protein Alignment Ae2 and slc4a9

DIOPT Version :9

• Sequence 1: NP_648357.1
• Gene: Ae2 / 39147
• FlyBaseID: FBgn0036043
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_012815206.2
• Gene: slc4a9 / 100498479
• XenbaseID: XB-GENE-990603
• Length: 997
• Species: Xenopus tropicalis
• Alignment Length: 1118
• Identity: 343/1118 - (30%)
• Similarity: 556/1118 - (49%)
• Gaps: 182/1118 - (16%)

  Fly   182 KLEENGDAGARRISVQPEDTALEEADLNELRSHRSDDPRALR-RHKIHHSSIKLRELPQITISPF 245
            ||.||            |.....:.:..:..:|.......|| .:.|..|....|.:....|||.
 Frog     2 KLGEN------------EGLVFRDVESAKFDNHSCGRSEGLRSTNSIIISQPANRSIFSNNISPT 54

  Fly   246 TNK---------KPEVDHSPHEIFVQLDELTGVGEDREWKETARWIKYEEDVEEGSDRWGKPHVA 301
            |.:         :.|.:.:...:|.||:||..|.|:.||:||||||::||..|:|.:||.||||.
 Frog    55 TEEVEFLFGEQGEGENEETHPLLFTQLNELFTVHENVEWRETARWIRFEEKTEDGGERWSKPHVT 119

  Fly   302 SLSFHSLLNLRRCLETGVVLLDLNEKDLPAVAYRVVEQMVIEDLIDINDKPSVMRSLLLRHRHVN 366
            :||.|||..|:.|:|.|.:|||:.:.....:...|....:..:.|:..:|..::.  ||..:||
 Frog   120 TLSLHSLFELKTCIERGTLLLDIEKSTFKEILECVTNINIANNSINQEEKEKIIH--LLCQKHV- 181

  Fly   367 EHQGVLPFTKRKYNSYTSLQFLWMGADSAHQPYQQAQPPPRNLAKARRSICVT--SSAPPTAAML 429
             ||     ||                              ::..|....||::  ||.|
 Frog   182 -HQ-----TK------------------------------KSRRKTMAEICLSSCSSCP------ 204

  Fly   430 NVATATAAAAAIDHRRHSTMSYLGNLSGTDDKKIKIMPAAEIGGSKRSNELKIDMKDDMYSSSQE 494
              ..||:..:.|                           ||:                    |::
 Frog   205 --GRATSQKSTI---------------------------AEL--------------------SEK 220

  Fly   495 DLKKLQNDTILKRIPAGAEATTVLVGAVEFLEQPTIAFVRLSEGVLMPTLTEVPVPVRFMFVLLG 559
            .||:...:...|:||.|.||..:|||.|:||:||.::|:||.|..::.:||||.:|.||:|:|||
 Frog   221 PLKEQLLNRFRKKIPEGTEAANILVGEVDFLDQPFVSFIRLKEARVLGSLTEVVLPSRFIFILLG 285

  Fly   560 PRNFDLDYHEVGRSISTLMANEHFHSIAYKADDRKDLLSAINEFLDDSIVLPPGNWDRHDLLPFE 624
            |:.....|||:||:|:||:.:|.|...||||..|..||:.|:||||:..:||||.||     |..
 Frog   286 PKIKTKAYHEIGRAIATLLTDELFQKTAYKALSRSGLLAGIDEFLDELSILPPGKWD-----PTV 345

  Fly   625 ELKAKKDWIRTRKIKALQVKRDSEMIKIGKDEEKALLEKQTLGAIGFTIGGGDGGGDGDSDDDNG 689
            .::..|......|.|.:.::                         |..:..|:.|.....::...
 Frog   346 RIQPPKFLPSPHKRKLMLLR-------------------------GNKLPCGENGNAFHQEEKLA 385

  Fly   690 RKKKKPS-PLEKTGRLWGGLRNDLKRRMPMYKSDILDGLNTETLAATIFMYFACLSTAITFGGLV 753
            ......| .|::|||::|||..|:||:.|.|.||..||||.:.|::.:|:|...::.:|||||::
 Frog   386 HGHPHASEELKRTGRIFGGLIKDVKRKAPWYWSDFYDGLNMQCLSSILFIYLVTVTNSITFGGML 450

  Fly   754 SAKTNSWIGISETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQHEFDFLSLRVY 818
            ...|::..|:.|..:..::.|.:|...|.|||.|:.:|||:|:|:..|..|...:||::|..|::
 Frog   451 GDATDNMQGVLENFLGTAISGGLFCLFSGQPLTILSSTGPVLVFERLLFRFSKDYEFEYLEFRLW 515

  Fly   819 VGVWLIIIALTVSAFEGSVYVRLLTRFTQEIFSALITLIYIVETFMKLISIYRENPLLSDYNLPP 883
            :|:|:....|.:.|.:.|..|:..||||:|.|.|||:||:|.:...|::::..:.|:..:|::..
 Frog   516 IGLWVAFYCLILVATDASYLVQYFTRFTEESFCALISLIFIYDAIKKMLNLADQFPINWEYSINH 580

  Fly   884 PTLVAHEHATNESLLNATASVTTNITQMVMNISTTAMPI-GPPPLPKNQ---------------- 931
            .|    :::...||.:.....:.|.|....|.|:....| ....|.:||
 Frog   581 MT----QYSCQCSLSDFGNYTSVNSTMYSSNNSSLYEKIEDSSNLTRNQCLEYGGHLVGSSCNYV 641

  Fly   932 PNTALFCTILTLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLVDYLVPAVYTEKL 996
            |:..|...:|...||..:..||.|::|.:|..:.|:..|||.|.::|.:|..:|... .:.|.||
 Frog   642 PDICLMSAMLFFGTFFCSSSLKQFQSSRYLSASIRKLAGDFSVILTILVFCAIDASF-GLETPKL 705

  Fly   997 VVPEGLSPSDPSKRGWYI-GFDTSSTWIPFACVIPALLVYILIFMESQISELIVDKPDRGLKKGS 1060
            :||....|::|: |.|.: .|..:..|:.....|||:|:.||:||:.||:.:|:::.:..|:||:
 Frog   706 IVPTEFKPTNPN-RSWIVTPFGKNPWWVCLLSGIPAILITILLFMDQQITAVILNRKEYKLRKGA 769

  Fly  1061 GLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGESPRIVDVKEQRLSGFF 1125
            |.|.|...:.||.......|:||..:|||.|:.|:.|:.:.|.|.||||.|:.:.::|||:||..
 Frog   770 GFHLDFFCIALLIIITSFMGLPWFVSATVISLAHMDSLKMESNTSAPGEQPKFLGIREQRVSGLA 834

  Fly  1126 VCLMIGLSVLMAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRLYFMPVKHYPPTSYVKRLRP 1190
            |.::.|.||.::|:|:.|||.||:|:||.||:|::..:|..||::|..:|.||.|...:::.:..
 Frog   835 VFILTGASVFLSPVLKYIPMPVLYGIFLQMGMAALRSIQFLERVQLLAIPPKHQPDLIFLRHVPL 899

  Fly  1191 WKLHLFTTIQVLCLVLLWSVKSSQFSLAFPFFLIMMVPIRQNLTKLYKPEEMQALDG-------- 1247
            .|:||||.||..|||:||.:||:..::.||..|:.:|.:|:::...:...::..||.
 Frog   900 RKVHLFTFIQTACLVILWILKSTVAAIIFPLMLLALVGVRKSMEWFFSLHDLSWLDDILPAKEKI 964

  Fly  1248 -SEMKKNDDDEPD 1259
             .|.||.:.|..|
 Frog   965 VQEPKKEESDLSD 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ae2	NP_648357.1	ae	260..1267	CDD:273290	327/1030 (32%)
		Band_3_cyto	287..618	CDD:284893	103/332 (31%)
		HCO3_cotransp	698..1199	CDD:279322	178/518 (34%)
slc4a9	XP_012815206.2	Band_3_cyto	78..984	CDD:421404	327/1030 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265068at2759
OrthoFinder	1	1.000	-	-		FOG0000136
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010