DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and PEPR1

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_177451.1	Gene:	PEPR1 / 843639	AraportID:	AT1G73080	Length:	1123	Species:	Arabidopsis thaliana

Alignment Length:	695	Identity:	147/695 - (21%)
Similarity:	231/695 - (33%)	Gaps:	235/695 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PIGWRNFQCSE---VASLQ--------------------DLVDLGAENW-----HTLAIRNVQTE 67
            |..|....|.:   ||||.                    .::||...|:     .||........
plant    63 PCNWFGITCDDSKNVASLNFTRSRVSGQLGPEIGELKSLQILDLSTNNFSGTIPSTLGNCTKLAT 127

  Fly    68 LEVGSGENADHLANLLD----LD--------LTGAAPINVHTNGFSILPNLRQL-----NLSG-- 113
            |::.....:|.:.:.||    |:        |||..|.::..     :|.|:.|     ||:|
plant   128 LDLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFR-----IPKLQVLYLDYNNLTGPI 187

  Fly   114 ---CG----LVDIR--GNHFA---PE-----SALQRIDFSHNQM-----ELLDRDFFGNLRKLIY 156
               .|    ||::.  .|.|:   ||     |:||.:....|::     |.|  :..|||..|..
plant   188 PQSIGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHRNKLVGSLPESL--NLLGNLTTLFV 250

  Fly   157 AN---------------------FSHN--------ALKQCD----------------------LP 170
            .|                     .|:|        ||..|.                      |.
plant   251 GNNSLQGPVRFGSPNCKNLLTLDLSYNEFEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLK 315

  Fly   171 HMPLLNRLELGHNRL---VNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLS- 231
            ::.:||   |..|||   :.|..|.|..|..|.||||||:....:|...|..|..|:|..||.|
plant   316 NLTILN---LSENRLSGSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLRKLESLELFENRFSG 377

  Fly   232 SIGLETFQPLAQLRKLNLSQNALDALRP-----------------NVFGAVQ---NFVLHLQQLD 276
            .|.:|.::. ..|.:|.:.||.|....|                 :.:||:.   .....|:::|
plant   378 EIPIEIWKS-QSLTQLLVYQNNLTGELPVEMTEMKKLKIATLFNNSFYGAIPPGLGVNSSLEEVD 441

  Fly   277 LSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAAL 341
            ..||::............:|::|::..|.:....||......::|:..|:.|.:..:.| .|:..
plant   442 FIGNKLTGEIPPNLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFILRENNLSGLLP-EFSQD 505

  Fly   342 LNLDTLDLSYNNLE----------------FLEEQIFGGNTLPRMRRL------NLNGNRMKHLH 384
            .:|..||.:.||.|                .|....|.|...|::..|      ||:.|.::...
plant   506 HSLSFLDFNSNNFEGPIPGSLGSCKNLSSINLSRNRFTGQIPPQLGNLQNLGYMNLSRNLLEGSL 570

  Fly   385 PLAFSSLPFLEYLKLGHNELK-----------------------SLDVRMFAP-MRRLQKLHLGH 425
            |...|:...||...:|.|.|.                       |..:..|.| :::|..|.:..
plant   571 PAQLSNCVSLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQFLPELKKLSTLQIAR 635

  Fly   426 N-----------LLEEINLDV--------------LESLSSVQEILVDNNRLTFLAKVNVSFPNL 465
            |           |:|::..|:              |..|..:..:.:.||.||....|.....:|
plant   636 NAFGGEIPSSIGLIEDLIYDLDLSGNGLTGEIPAKLGDLIKLTRLNISNNNLTGSLSVLKGLTSL 700

  Fly   466 KRVAIEGNPWQCPCFVKLQHWLATRDVVYLRDNTGYYKGERPLCI 510
            ..|.:..|.:..|....|:..|.:        ....:.|...|||
plant   701 LHVDVSNNQFTGPIPDNLEGQLLS--------EPSSFSGNPNLCI 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	62/236 (26%)
		LRR_8	104..164	CDD:290566	26/117 (22%)
		leucine-rich repeat	106..129	CDD:275380	12/46 (26%)
		leucine-rich repeat	130..153	CDD:275380	8/27 (30%)
		leucine-rich repeat	154..195	CDD:275380	17/94 (18%)
		LRR_RI	194..455	CDD:238064	76/352 (22%)
		LRR_8	194..254	CDD:290566	22/60 (37%)
		leucine-rich repeat	196..219	CDD:275380	10/22 (45%)
		leucine-rich repeat	220..243	CDD:275380	8/23 (35%)
		leucine-rich repeat	244..267	CDD:275380	8/42 (19%)
		LRR_8	271..330	CDD:290566	12/58 (21%)
		leucine-rich repeat	272..295	CDD:275380	4/22 (18%)
		leucine-rich repeat	296..319	CDD:275380	5/22 (23%)
		LRR_8	319..380	CDD:290566	19/82 (23%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)
		leucine-rich repeat	344..369	CDD:275380	9/40 (23%)
		LRR_8	368..428	CDD:290566	18/100 (18%)
		leucine-rich repeat	370..393	CDD:275380	6/28 (21%)
		leucine-rich repeat	394..417	CDD:275380	8/46 (17%)
		leucine-rich repeat	418..441	CDD:275380	8/47 (17%)
PEPR1	NP_177451.1	PLN00113	47..1119	CDD:215061	147/695 (21%)
		leucine-rich repeat	77..100	CDD:275380	4/22 (18%)
		LRR_RI	90..280	CDD:238064	40/196 (20%)
		leucine-rich repeat	101..124	CDD:275380	5/22 (23%)
		leucine-rich repeat	125..148	CDD:275380	4/22 (18%)
		leucine-rich repeat	149..172	CDD:275380	5/27 (19%)
		leucine-rich repeat	173..196	CDD:275380	6/22 (27%)
		leucine-rich repeat	197..220	CDD:275380	6/22 (27%)
		leucine-rich repeat	221..254	CDD:275380	10/34 (29%)
		leucine-rich repeat	255..316	CDD:275380	6/60 (10%)
		leucine-rich repeat	317..340	CDD:275380	9/25 (36%)
		leucine-rich repeat	341..364	CDD:275380	10/22 (45%)
		leucine-rich repeat	389..436	CDD:275380	8/46 (17%)
		leucine-rich repeat	437..457	CDD:275380	4/19 (21%)
		leucine-rich repeat	461..484	CDD:275378	5/22 (23%)
		LRR_RI	490..711	CDD:238064	44/221 (20%)
		leucine-rich repeat	508..531	CDD:275380	6/22 (27%)
		leucine-rich repeat	532..555	CDD:275380	5/22 (23%)
		leucine-rich repeat	556..579	CDD:275380	5/22 (23%)
		leucine-rich repeat	580..603	CDD:275380	5/22 (23%)
		leucine-rich repeat	604..627	CDD:275380	3/22 (14%)
		leucine-rich repeat	628..651	CDD:275380	4/22 (18%)
		leucine-rich repeat	652..676	CDD:275380	3/23 (13%)
		leucine-rich repeat	677..699	CDD:275380	5/21 (24%)
		leucine-rich repeat	700..720	CDD:275380	5/19 (26%)
		PKc_like	833..1110	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910