DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6749 and BRL1

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001117501.1	Gene:	BRL1 / 842010	AraportID:	AT1G55610	Length:	1166	Species:	Arabidopsis thaliana

Alignment Length:	638	Identity:	149/638 - (23%)
Similarity:	221/638 - (34%)	Gaps:	215/638 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WVLPLLLWL----LCMGFPILHGADLCQ-----------------------------------PI 32
            |:|.|:|..    |.||   :||..|..                                   ..
plant     5 WLLVLILCFFTTSLVMG---IHGKHLINDDFNETALLLAFKQNSVKSDPNNVLGNWKYESGRGSC 66

  Fly    33 GWRNFQCSEVASLQDLVDL------GAENWHTL-AIRNVQTEL-------EVGSGENADHLANLL 83
            .||...||:...:..| ||      |..|...| |:.|:|...       ..|....:|....:|
plant    67 SWRGVSCSDDGRIVGL-DLRNSGLTGTLNLVNLTALPNLQNLYLQGNYFSSGGDSSGSDCYLQVL 130

  Fly    84 DLDLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPES--ALQRIDFSHNQM-----E 141
            ||.....:..::....||...||..:|:|...||...|  |||.|  :|..:|.|:|.:     |
plant   131 DLSSNSISDYSMVDYVFSKCSNLVSVNISNNKLVGKLG--FAPSSLQSLTTVDLSYNILSDKIPE 193

  Fly   142 LLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILNDNQL 206
            ....||..:|:   |.:.:||.|.                 ....:.:||:|..|....|:.|
plant   194 SFISDFPASLK---YLDLTHNNLS-----------------GDFSDLSFGICGNLTFFSLSQN-- 236

  Fly   207 IQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPN--VFGAVQNFV 269
                             .|||::...    |......|..||:|:|.|....||  .:|:.||
plant   237 -----------------NLSGDKFPI----TLPNCKFLETLNISRNNLAGKIPNGEYWGSFQN-- 278

  Fly   270 LHLQQLDLSGNRIRLLFDNQFRVLAR-LQMLDVSRNSIASLSPAHF--------VGLGS------ 319
              |:||.|:.||:......:..:|.: |.:||:|.|:.:...|:.|        :.||:
plant   279 --LKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNYLSGD 341

  Fly   320 -----------LRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGN-------- 365
                       :..||:.||.|....|.:.....||..||||.|.        |.||
plant   342 FLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLSSNG--------FTGNVPSGFCSL 398

  Fly   366 -TLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNEL-----KSL-------DVRMFA---- 413
             :.|.:.::.:..|.:....|:.......|:.:.|..|||     |.:       |:.|:|
plant   399 QSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDLSFNELTGPIPKEIWMLPNLSDLVMWANNLT 463

  Fly   414 ---------PMRRLQKLHLGHNLLEEINLDVLESLSSVQEIL---VDNNRLTFLAKVNVSFPNLK 466
                     ....|:.|.|.:|||..   .:.||:|....::   :.:||||  .|:.....||.
plant   464 GTIPEGVCVKGGNLETLILNNNLLTG---SIPESISRCTNMIWISLSSNRLT--GKIPSGIGNLS 523

  Fly   467 RVAI--------EGN-PWQ---CPCFVKLQHWLATRDVVYLRDN--TGYYKGE 505
            ::||        .|| |.|   |...:    ||.      |..|  ||...||
plant   524 KLAILQLGNNSLSGNVPRQLGNCKSLI----WLD------LNSNNLTGDLPGE 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	39/159 (25%)
		LRR_8	104..164	CDD:290566	22/66 (33%)
		leucine-rich repeat	106..129	CDD:275380	10/24 (42%)
		leucine-rich repeat	130..153	CDD:275380	8/27 (30%)
		leucine-rich repeat	154..195	CDD:275380	7/40 (18%)
		LRR_RI	194..455	CDD:238064	75/325 (23%)
		LRR_8	194..254	CDD:290566	12/59 (20%)
		leucine-rich repeat	196..219	CDD:275380	3/22 (14%)
		leucine-rich repeat	220..243	CDD:275380	4/22 (18%)
		leucine-rich repeat	244..267	CDD:275380	9/24 (38%)
		LRR_8	271..330	CDD:290566	20/84 (24%)
		leucine-rich repeat	272..295	CDD:275380	7/22 (32%)
		leucine-rich repeat	296..319	CDD:275380	8/30 (27%)
		LRR_8	319..380	CDD:290566	18/86 (21%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..369	CDD:275380	9/33 (27%)
		LRR_8	368..428	CDD:290566	16/84 (19%)
		leucine-rich repeat	370..393	CDD:275380	2/22 (9%)
		leucine-rich repeat	394..417	CDD:275380	9/47 (19%)
		leucine-rich repeat	418..441	CDD:275380	8/22 (36%)
BRL1	NP_001117501.1	PLN00113	33..1125	CDD:215061	139/607 (23%)
		leucine-rich repeat	104..125	CDD:275380	2/20 (10%)
		LRR_RI	<125..318	CDD:238064	61/241 (25%)
		leucine-rich repeat	127..152	CDD:275380	5/24 (21%)
		leucine-rich repeat	153..176	CDD:275380	10/24 (42%)
		leucine-rich repeat	177..202	CDD:275380	7/24 (29%)
		leucine-rich repeat	203..227	CDD:275380	8/43 (19%)
		leucine-rich repeat	228..278	CDD:275380	16/72 (22%)
		leucine-rich repeat	279..303	CDD:275380	7/23 (30%)
		LRR_RI	298..569	CDD:238064	69/292 (24%)
		leucine-rich repeat	304..330	CDD:275380	7/25 (28%)
		leucine-rich repeat	331..376	CDD:275380	8/44 (18%)
		leucine-rich repeat	332..352	CDD:275380	2/19 (11%)
		leucine-rich repeat	377..400	CDD:275380	9/30 (30%)
		leucine-rich repeat	404..427	CDD:275380	2/22 (9%)
		leucine-rich repeat	428..451	CDD:275380	6/22 (27%)
		leucine-rich repeat	452..476	CDD:275380	3/23 (13%)
		leucine-rich repeat	477..500	CDD:275380	9/25 (36%)
		leucine-rich repeat	501..524	CDD:275380	7/24 (29%)
		leucine-rich repeat	525..546	CDD:275380	6/20 (30%)
		leucine-rich repeat	549..664	CDD:275380	8/28 (29%)
		leucine-rich repeat	612..660	CDD:275380
		leucine-rich repeat	665..688	CDD:275380
		leucine-rich repeat	689..710	CDD:275380
		PKc_like	865..1136	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910