DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and PXY

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_200956.1	Gene:	PXY / 836269	AraportID:	AT5G61480	Length:	1041	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	112/494 - (22%)
Similarity:	174/494 - (35%)	Gaps:	125/494 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SGENADHL-ANLLDLD-----LTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESAL 130
            ||...|:: |.::.||     |:|..||.:.     .|.:|..|||||..|...........:.|
plant    72 SGVVCDNVTAQVISLDLSHRNLSGRIPIQIR-----YLSSLLYLNLSGNSLEGSFPTSIFDLTKL 131

  Fly   131 QRIDFSHNQMELLDRDFFGNLRKL----IYANFSHN--ALKQCDLPHMPLLNRLELGHNRL---V 186
            ..:|.|.|.   .|..|...:.||    ::..||:|  .|...|:..:..|..|..|.:..   :
plant   132 TTLDISRNS---FDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSYFEGEI 193

  Fly   187 NATFGVCPQLQEL----------------ILNDNQLIQLDVNAFRG--------LHGLLELQLSG 227
            .|.:|...:|:.:                :|.:.|.:::..|.|.|        |..|....:|.
plant   194 PAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSN 258

  Fly   228 NRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRV 292
            ..||....:....|:.|..|.|.||......|..:..:::    |:.||.|.|::.....:.|..
plant   259 CSLSGSLPQELGNLSNLETLFLFQNGFTGEIPESYSNLKS----LKLLDFSSNQLSGSIPSGFST 319

  Fly   293 LARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLE-- 355
            |..|..|.:..|:::...|.....|..|..|:|..|....:.|....:...|:|:|:|.|:..
plant   320 LKNLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGT 384

  Fly   356 --------------FLEEQIFGGNTLPR-------MRRLNLNGNRMKHLHPLAFSSLPFLEYLKL 399
                          .|...:|.|. ||:       :.|.....||:....|:.|.||..|.::.|
plant   385 IPSSLCHGNKLYKLILFSNMFEGE-LPKSLTRCESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDL 448

  Fly   400 GHNELKSLDVRMFAPMRRLQKLHLGHN-----LLEEI----NLDVLESLSSVQEILVDNNRLTFL 455
            .:|.........||....||.|:|..|     |.|.|    ||.:.
plant   449 SNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIF------------------- 494

  Fly   456 AKVNVSFPNL-------------KRVAIEGN------PW 475
               :.||.||             .|:.::||      ||
plant   495 ---SASFSNLIGEIPNYVGCKSFYRIELQGNSLNGTIPW 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	43/185 (23%)
		LRR_8	104..164	CDD:290566	18/65 (28%)
		leucine-rich repeat	106..129	CDD:275380	7/22 (32%)
		leucine-rich repeat	130..153	CDD:275380	6/22 (27%)
		leucine-rich repeat	154..195	CDD:275380	11/49 (22%)
		LRR_RI	194..455	CDD:238064	67/316 (21%)
		LRR_8	194..254	CDD:290566	17/83 (20%)
		leucine-rich repeat	196..219	CDD:275380	7/46 (15%)
		leucine-rich repeat	220..243	CDD:275380	5/22 (23%)
		leucine-rich repeat	244..267	CDD:275380	6/22 (27%)
		LRR_8	271..330	CDD:290566	16/58 (28%)
		leucine-rich repeat	272..295	CDD:275380	7/22 (32%)
		leucine-rich repeat	296..319	CDD:275380	5/22 (23%)
		LRR_8	319..380	CDD:290566	17/83 (20%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)
		leucine-rich repeat	344..369	CDD:275380	9/40 (23%)
		LRR_8	368..428	CDD:290566	18/71 (25%)
		leucine-rich repeat	370..393	CDD:275380	7/22 (32%)
		leucine-rich repeat	394..417	CDD:275380	5/22 (23%)
		leucine-rich repeat	418..441	CDD:275380	10/31 (32%)
PXY	NP_200956.1	PLN00113	61..1000	CDD:215061	112/494 (23%)
		leucine-rich repeat	85..106	CDD:275380	7/25 (28%)
		leucine-rich repeat	107..130	CDD:275380	7/22 (32%)
		leucine-rich repeat	131..162	CDD:275380	8/33 (24%)
		leucine-rich repeat	155..178	CDD:275378	5/22 (23%)
		leucine-rich repeat	203..226	CDD:275380	2/22 (9%)
		leucine-rich repeat	227..250	CDD:275380	5/22 (23%)
		leucine-rich repeat	251..274	CDD:275380	5/22 (23%)
		leucine-rich repeat	275..298	CDD:275380	6/22 (27%)
		leucine-rich repeat	299..322	CDD:275380	7/22 (32%)
		leucine-rich repeat	323..346	CDD:275380	5/22 (23%)
		leucine-rich repeat	347..370	CDD:275380	5/22 (23%)
		leucine-rich repeat	371..394	CDD:275380	5/22 (23%)
		leucine-rich repeat	395..418	CDD:275380	5/23 (22%)
		leucine-rich repeat	419..442	CDD:275380	7/22 (32%)
		leucine-rich repeat	443..462	CDD:275380	3/18 (17%)
		leucine-rich repeat	467..537	CDD:275380	19/86 (22%)
		leucine-rich repeat	491..513	CDD:275378	5/43 (12%)
		leucine-rich repeat	538..561	CDD:275380
		leucine-rich repeat	562..582	CDD:275380
		leucine-rich repeat	586..608	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910