DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and AT5G19680

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_197469.1	Gene:	AT5G19680 / 832088	AraportID:	AT5G19680	Length:	328	Species:	Arabidopsis thaliana

Alignment Length:	324	Identity:	82/324 - (25%)
Similarity:	153/324 - (47%)	Gaps:	68/324 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 LDVNAFRGLH---------GLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALD--ALRP-NV 261
            ||:.::: ||         .|:||.|:.||||.:.....| |:.|:||:|.||.:|  |:.| :.
plant    20 LDLTSYQ-LHSLDTVELPPNLIELDLTANRLSGLDSRIAQ-LSTLKKLSLRQNLIDDSAVEPLSH 82

  Fly   262 FGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGL----GSLRK 322
            :.|:.:    |::|.|..|::..:.|  ..:..:|.:.|:|.|.|.||.     |:    .:|::
plant    83 WDALSD----LEELVLRDNKLAKVPD--VSIFTKLLVYDISFNEITSLE-----GISKASSTLKE 136

  Fly   323 LYL---QYNAILEIKPATFAALLNLDTLDLSYNNLEFLE--------EQIFGGNT---------L 367
            ||:   :.|.|:||:     .|.||..|:|..|.|..:|        |:::.|..         |
plant   137 LYVSKNEVNKIMEIE-----HLHNLQILELGSNRLRVMENLENFTKLEELWLGRNRIKVVNLCGL 196

  Fly   368 PRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEIN 432
            ..:::::|..||:..:.  .|.....||.|.|.||.:..::  ..:.:..|:.|.:.:|.|..:
plant   197 KCIKKISLQSNRLTSMK--GFEECVALEELYLSHNGISKME--GLSALVNLRVLDVSNNKLTSV- 256

  Fly   433 LDVLESLSSVQEILVDNNRLTFL----AKVNVSFPNLKRVAIEGNPWQCPCFVKLQHWLATRDV 492
             |.:::|:.::::.:::|::..|    ..|..|...|..:.:|.|    ||.....:..|.|.:
plant   257 -DDIQNLTKLEDLWLNDNQIESLEAITEAVTGSKEKLTTIYLENN----PCAKSSDYVAAVRQI 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	21/57 (37%)
		LRR_8	104..164	CDD:290566
		leucine-rich repeat	106..129	CDD:275380
		leucine-rich repeat	130..153	CDD:275380
		leucine-rich repeat	154..195	CDD:275380
		LRR_RI	194..455	CDD:238064	72/281 (26%)
		LRR_8	194..254	CDD:290566	20/53 (38%)
		leucine-rich repeat	196..219	CDD:275380	4/18 (22%)
		leucine-rich repeat	220..243	CDD:275380	10/22 (45%)
		leucine-rich repeat	244..267	CDD:275380	10/25 (40%)
		LRR_8	271..330	CDD:290566	17/65 (26%)
		leucine-rich repeat	272..295	CDD:275380	5/22 (23%)
		leucine-rich repeat	296..319	CDD:275380	8/26 (31%)
		LRR_8	319..380	CDD:290566	20/80 (25%)
		leucine-rich repeat	320..343	CDD:275380	8/25 (32%)
		leucine-rich repeat	344..369	CDD:275380	9/41 (22%)
		LRR_8	368..428	CDD:290566	13/59 (22%)
		leucine-rich repeat	370..393	CDD:275380	4/22 (18%)
		leucine-rich repeat	394..417	CDD:275380	6/22 (27%)
		leucine-rich repeat	418..441	CDD:275380	6/22 (27%)
AT5G19680	NP_197469.1	leucine-rich repeat	19..38	CDD:275380	4/18 (22%)
		internalin_A	<20..>183	CDD:380193	53/180 (29%)
		leucine-rich repeat	39..61	CDD:275380	10/22 (45%)
		leucine-rich repeat	62..88	CDD:275380	10/25 (40%)
		leucine-rich repeat	89..110	CDD:275380	5/22 (23%)
		leucine-rich repeat	111..133	CDD:275380	8/26 (31%)
		PPP1R42	121..308	CDD:411060	47/206 (23%)
		leucine-rich repeat	134..155	CDD:275380	8/25 (32%)
		leucine-rich repeat	156..177	CDD:275380	6/20 (30%)
		leucine-rich repeat	178..198	CDD:275380	3/19 (16%)
		leucine-rich repeat	199..220	CDD:275380	4/22 (18%)
		leucine-rich repeat	221..242	CDD:275380	6/22 (27%)
		leucine-rich repeat	243..264	CDD:275380	6/22 (27%)
		leucine-rich repeat	265..291	CDD:275380	4/25 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910