DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and AT5G12940

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_196798.1	Gene:	AT5G12940 / 831134	AraportID:	AT5G12940	Length:	371	Species:	Arabidopsis thaliana

Alignment Length:	408	Identity:	90/408 - (22%)
Similarity:	146/408 - (35%)	Gaps:	110/408 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GADLCQPIGWRNFQCSEVASLQDLVDLGAENWHTLAIRNVQTELEVGSGENADHL---ANLLDLD 86
            |.|.|:  ||....|..               :|..:..:...     ||:.|.|   |....|
plant    55 GLDCCK--GWYGVSCDP---------------NTRRVAGITLR-----GESEDPLFQKAKRSGL- 96

  Fly    87 LTGAAPINVHTNGFSILPNLRQL-NLSGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGN 150
            :||           ||.|::.:| .|||..:.|.:|
plant    97 MTG-----------SISPSICKLTRLSGIIIADWKG----------------------------- 121

  Fly   151 LRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILNDNQLIQLDVNAFR 215
                     ....:..| :.::|.|..|:|..|:.    .||.|      .|..:|::|.|
plant   122 ---------ISGVIPSC-IENLPFLRHLDLVGNKF----SGVIP------ANIGKLLRLKV---- 162

  Fly   216 GLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGN 280
                   |.|:.|.|..:...:...|..|..|:|..|.:..:.|...|.::    .:.::.||||
plant   163 -------LNLADNHLYGVIPPSITRLVSLSHLDLRNNNISGVIPRDIGRLK----MVSRVLLSGN 216

  Fly   281 RIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLD 345
            :|.....:....:.||..|::|.|.:....||.|..:..|..|.|..|.|..:.|.:..| .::.
plant   217 KISGQIPDSLTRIYRLADLELSMNRLTGPIPASFGKMSVLATLNLDGNLISGMIPGSLLA-SSIS 280

  Fly   346 TLDLSYNNLEFLEEQIFGGNTLPR--MRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLD 408
            .|:||.|.:.......||    ||  ...|:|..||::...|.:.::..|:.:|.:.||.|.. .
plant   281 NLNLSGNLITGSIPNTFG----PRSYFTVLDLANNRLQGPIPASITAASFIGHLDVSHNHLCG-K 340

  Fly   409 VRMFAPMRRLQKLHLGHN 426
            :.|.:|...|......:|
plant   341 IPMGSPFDHLDATSFAYN 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	29/153 (19%)
		LRR_8	104..164	CDD:290566	7/60 (12%)
		leucine-rich repeat	106..129	CDD:275380	6/23 (26%)
		leucine-rich repeat	130..153	CDD:275380	0/22 (0%)
		leucine-rich repeat	154..195	CDD:275380	8/40 (20%)
		LRR_RI	194..455	CDD:238064	58/235 (25%)
		LRR_8	194..254	CDD:290566	14/59 (24%)
		leucine-rich repeat	196..219	CDD:275380	4/22 (18%)
		leucine-rich repeat	220..243	CDD:275380	5/22 (23%)
		leucine-rich repeat	244..267	CDD:275380	6/22 (27%)
		LRR_8	271..330	CDD:290566	17/58 (29%)
		leucine-rich repeat	272..295	CDD:275380	5/22 (23%)
		leucine-rich repeat	296..319	CDD:275380	7/22 (32%)
		LRR_8	319..380	CDD:290566	18/62 (29%)
		leucine-rich repeat	320..343	CDD:275380	7/22 (32%)
		leucine-rich repeat	344..369	CDD:275380	6/24 (25%)
		LRR_8	368..428	CDD:290566	16/61 (26%)
		leucine-rich repeat	370..393	CDD:275380	5/22 (23%)
		leucine-rich repeat	394..417	CDD:275380	6/22 (27%)
		leucine-rich repeat	418..441	CDD:275380	2/9 (22%)
AT5G12940	NP_196798.1	PLN00113	35..>344	CDD:215061	86/392 (22%)
		leucine-rich repeat	136..159	CDD:275380	9/32 (28%)
		leucine-rich repeat	160..183	CDD:275380	7/33 (21%)
		leucine-rich repeat	184..207	CDD:275380	6/26 (23%)
		leucine-rich repeat	208..231	CDD:275380	5/22 (23%)
		leucine-rich repeat	232..255	CDD:275380	7/22 (32%)
		leucine-rich repeat	256..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	8/26 (31%)
		leucine-rich repeat	303..322	CDD:275380	5/18 (28%)
		leucine-rich repeat	329..350	CDD:275380	6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910