DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and BAM3

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_193760.1	Gene:	BAM3 / 827774	AraportID:	AT4G20270	Length:	992	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	135/574 - (23%)
Similarity:	200/574 - (34%)	Gaps:	215/574 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLCMGFPILHGADLCQPIGWRNF-QCSEVASLQ---DLVDLGAENWHTLAIRNVQTELEVGSGEN 75
            |||        :.|..|:..... |.:.:.||:   |..|...::|:   |.|..: |...:|.:
plant    18 LLC--------SSLISPLNLSLIRQANVLISLKQSFDSYDPSLDSWN---IPNFNS-LCSWTGVS 70

  Fly    76 ADHL-ANLLDLDLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQ 139
            .|:| .::..|||:     |::.:| :|.|.:.:|:.|                 |..:|.|.|
plant    71 CDNLNQSITRLDLS-----NLNISG-TISPEISRLSPS-----------------LVFLDISSN- 111

  Fly   140 MELLDRDFFGNLRKLIY-------ANFSHNALKQCDLPHMPLLNRLEL-GHNRLVNATFGVCPQL 196
                  .|.|.|.|.||       .|.|.|..:          ..||. |.:::
plant   112 ------SFSGELPKEIYELSGLEVLNISSNVFE----------GELETRGFSQM----------- 149

  Fly   197 QELILNDNQLIQLDV--NAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRP 259
                   .||:.||.  |:|   :|.|.|.|:             .|.:|..|:|..|..|...|
plant   150 -------TQLVTLDAYDNSF---NGSLPLSLT-------------TLTRLEHLDLGGNYFDGEIP 191

  Fly   260 NVFGAVQNFVLHLQQLDLSGNRIRLLFDNQ-------------------------FRVLARLQML 299
            ..:|:    .|.|:.|.||||.:|....|:                         |..|..|..|
plant   192 RSYGS----FLSLKFLSLSGNDLRGRIPNELANITTLVQLYLGYYNDYRGGIPADFGRLINLVHL 252

  Fly   300 DVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQI--- 361
            |::..|:....||....|.:|..|:||.|.:....|.....:.:|.|||||.|   |||.:|
plant   253 DLANCSLKGSIPAELGNLKNLEVLFLQTNELTGSVPRELGNMTSLKTLDLSNN---FLEGEIPLE 314

  Fly   362 FGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHN--------------ELKSLDVR-- 410
            ..|  |.:::..||..||:....|...|.||.|:.|||.||              .|..:|:.
plant   315 LSG--LQKLQLFNLFFNRLHGEIPEFVSELPDLQILKLWHNNFTGKIPSKLGSNGNLIEIDLSTN 377

  Fly   411 -------------------------MFAPM-------RRLQKLHLGHNLLEE---------INLD 434
                                     :|.|:       ..|.:..||.|.|..         .||.
plant   378 KLTGLIPESLCFGRRLKILILFNNFLFGPLPEDLGQCEPLWRFRLGQNFLTSKLPKGLIYLPNLS 442

  Fly   435 VLE------------------SLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAI 470
            :||                  ..||:.:|.:.||||:  ..:..|..||:.:.|
plant   443 LLELQNNFLTGEIPEEEAGNAQFSSLTQINLSNNRLS--GPIPGSIRNLRSLQI 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	34/162 (21%)
		LRR_8	104..164	CDD:290566	16/66 (24%)
		leucine-rich repeat	106..129	CDD:275380	2/22 (9%)
		leucine-rich repeat	130..153	CDD:275380	7/22 (32%)
		leucine-rich repeat	154..195	CDD:275380	8/48 (17%)
		LRR_RI	194..455	CDD:238064	89/365 (24%)
		LRR_8	194..254	CDD:290566	15/61 (25%)
		leucine-rich repeat	196..219	CDD:275380	6/24 (25%)
		leucine-rich repeat	220..243	CDD:275380	4/22 (18%)
		leucine-rich repeat	244..267	CDD:275380	7/22 (32%)
		LRR_8	271..330	CDD:290566	22/83 (27%)
		leucine-rich repeat	272..295	CDD:275380	10/47 (21%)
		leucine-rich repeat	296..319	CDD:275380	7/22 (32%)
		LRR_8	319..380	CDD:290566	22/63 (35%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..369	CDD:275380	13/27 (48%)
		LRR_8	368..428	CDD:290566	22/107 (21%)
		leucine-rich repeat	370..393	CDD:275380	7/22 (32%)
		leucine-rich repeat	394..417	CDD:275380	10/70 (14%)
		leucine-rich repeat	418..441	CDD:275380	9/49 (18%)
BAM3	NP_193760.1	LRRNT_2	34..72	CDD:285463	10/41 (24%)
		PLN00113	37..986	CDD:215061	129/547 (24%)
		leucine-rich repeat	79..102	CDD:275380	8/28 (29%)
		leucine-rich repeat	103..126	CDD:275380	10/29 (34%)
		leucine-rich repeat	127..151	CDD:275380	6/51 (12%)
		leucine-rich repeat	152..175	CDD:275380	10/38 (26%)
		leucine-rich repeat	176..199	CDD:275380	7/26 (27%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		leucine-rich repeat	224..248	CDD:275380	2/23 (9%)
		leucine-rich repeat	249..272	CDD:275380	7/22 (32%)
		LRR_RI	270..574	CDD:238064	58/232 (25%)
		leucine-rich repeat	273..296	CDD:275380	6/22 (27%)
		leucine-rich repeat	297..318	CDD:275380	12/25 (48%)
		leucine-rich repeat	321..344	CDD:275380	7/22 (32%)
		leucine-rich repeat	345..368	CDD:275380	6/22 (27%)
		leucine-rich repeat	369..392	CDD:275380	2/22 (9%)
		leucine-rich repeat	393..414	CDD:275380	2/20 (10%)
		leucine-rich repeat	441..467	CDD:275380	3/25 (12%)
		leucine-rich repeat	468..491	CDD:275380	8/24 (33%)
		leucine-rich repeat	492..513	CDD:275380	1/3 (33%)
		leucine-rich repeat	564..587	CDD:275380
		PKc_like	716..984	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910