DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and BRL3

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_187946.1	Gene:	BRL3 / 820538	AraportID:	AT3G13380	Length:	1164	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	132/552 - (23%)
Similarity:	197/552 - (35%)	Gaps:	191/552 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GADLCQPIGWRNFQCSEVASLQDLVDLGAENWHTLAIRNVQTELEVGSGENADHLANLLDLDLTG 89
            |.|.|.   ||...||...                  |.:..:|..|.              |||
plant    61 GRDPCT---WRGVSCSSDG------------------RVIGLDLRNGG--------------LTG 90

  Fly    90 AAPINVHTNGFSILPNLRQLNL-------------SGCGL--VDIRGNHFAPESA---------- 129
                .::.|..:.|.|||.|.|             |||.|  :|:..|.....|.
plant    91 ----TLNLNNLTALSNLRSLYLQGNNFSSGDSSSSSGCSLEVLDLSSNSLTDSSIVDYVFSTCLN 151

  Fly   130 LQRIDFSHNQM------------------ELLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLN 176
            |..::||||::                  :|.:..|...:.:...|:|. |:||..||..    |
plant   152 LVSVNFSHNKLAGKLKSSPSASNKRITTVDLSNNRFSDEIPETFIADFP-NSLKHLDLSG----N 211

  Fly   177 RLELGHNRLVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNR----LSSIGLET 237
            .:....:||   :||:|..|....|:.|                   .:||:|    ||:..|
plant   212 NVTGDFSRL---SFGLCENLTVFSLSQN-------------------SISGDRFPVSLSNCKL-- 252

  Fly   238 FQPLAQLRKLNLSQNALDALRP--NVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLAR-LQML 299
                  |..||||:|:|....|  :.:|..||    |:||.|:.|........:..:|.| |::|
plant   253 ------LETLNLSRNSLIGKIPGDDYWGNFQN----LRQLSLAHNLYSGEIPPELSLLCRTLEVL 307

  Fly   300 DVSRNSIASLSPAHFVGLGSLR-------------------------KLYLQYNAILEIKPATFA 339
            |:|.||:....|..|...|||:                         .|||.:|.|....|.:..
plant   308 DLSGNSLTGQLPQSFTSCGSLQSLNLGNNKLSGDFLSTVVSKLSRITNLYLPFNNISGSVPISLT 372

  Fly   340 ALLNLDTLDLSYNNLEF----------------LEEQIFGGN----TLP-------RMRRLNLNG 377
            ...||..||||.|  ||                ||:.:...|    |:|       .::.::|:.
plant   373 NCSNLRVLDLSSN--EFTGEVPSGFCSLQSSSVLEKLLIANNYLSGTVPVELGKCKSLKTIDLSF 435

  Fly   378 NRMKHLHPLAFSSLPFLEYLKLGHNELK-SLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSS 441
            |.:..|.|....:||.|..|.:..|.|. .:...:......|:.|.|.:|||..   .:.||:|.
plant   436 NALTGLIPKEIWTLPKLSDLVMWANNLTGGIPESICVDGGNLETLILNNNLLTG---SLPESISK 497

  Fly   442 VQEIL---VDNNRLTFLAKVNVSFPNLKRVAI 470
            ...:|   :.:|.||  .::.|....|:::||
plant   498 CTNMLWISLSSNLLT--GEIPVGIGKLEKLAI 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	49/199 (25%)
		LRR_8	104..164	CDD:290566	22/102 (22%)
		leucine-rich repeat	106..129	CDD:275380	10/37 (27%)
		leucine-rich repeat	130..153	CDD:275380	7/40 (18%)
		leucine-rich repeat	154..195	CDD:275380	13/40 (33%)
		LRR_RI	194..455	CDD:238064	81/323 (25%)
		LRR_8	194..254	CDD:290566	15/63 (24%)
		leucine-rich repeat	196..219	CDD:275380	3/22 (14%)
		leucine-rich repeat	220..243	CDD:275380	6/26 (23%)
		leucine-rich repeat	244..267	CDD:275380	9/24 (38%)
		LRR_8	271..330	CDD:290566	22/84 (26%)
		leucine-rich repeat	272..295	CDD:275380	6/22 (27%)
		leucine-rich repeat	296..319	CDD:275380	8/22 (36%)
		LRR_8	319..380	CDD:290566	24/112 (21%)
		leucine-rich repeat	320..343	CDD:275380	7/47 (15%)
		leucine-rich repeat	344..369	CDD:275380	13/51 (25%)
		LRR_8	368..428	CDD:290566	15/67 (22%)
		leucine-rich repeat	370..393	CDD:275380	5/22 (23%)
		leucine-rich repeat	394..417	CDD:275380	4/23 (17%)
		leucine-rich repeat	418..441	CDD:275380	8/22 (36%)
BRL3	NP_187946.1	PLN00113	32..1123	CDD:215061	132/552 (24%)
		leucine-rich repeat	81..102	CDD:275380	7/38 (18%)
		leucine-rich repeat	126..151	CDD:275380	4/24 (17%)
		leucine-rich repeat	152..176	CDD:275380	5/23 (22%)
		leucine-rich repeat	177..202	CDD:275380	4/25 (16%)
		leucine-rich repeat	203..227	CDD:275380	10/30 (33%)
		leucine-rich repeat	228..252	CDD:275380	8/42 (19%)
		leucine-rich repeat	279..303	CDD:275380	6/23 (26%)
		leucine-rich repeat	304..327	CDD:275380	8/22 (36%)
		leucine-rich repeat	328..352	CDD:275380	1/23 (4%)
		leucine-rich repeat	353..376	CDD:275380	6/22 (27%)
		leucine-rich repeat	377..400	CDD:275380	8/24 (33%)
		leucine-rich repeat	404..427	CDD:275380	5/22 (23%)
		leucine-rich repeat	428..451	CDD:275380	5/22 (23%)
		leucine-rich repeat	452..476	CDD:275380	4/23 (17%)
		leucine-rich repeat	477..500	CDD:275380	9/25 (36%)
		leucine-rich repeat	501..524	CDD:275380	6/24 (25%)
		leucine-rich repeat	525..546	CDD:275380	2/3 (67%)
		leucine-rich repeat	549..640	CDD:275380
		leucine-rich repeat	641..664	CDD:275380
		leucine-rich repeat	665..688	CDD:275380
		leucine-rich repeat	689..712	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910