DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and PIRL5

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_179336.1	Gene:	PIRL5 / 816250	AraportID:	AT2G17440	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	316	Identity:	92/316 - (29%)
Similarity:	151/316 - (47%)	Gaps:	40/316 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 ESALQRIDFSHNQMELLD--RDFFGNLRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNAT 189
            :.|.|.::..|..|:.|:  .|..|.|..|:..:.|.|.:                   .::.||
plant   203 KKATQELNLQHRLMDQLEWLPDSLGKLSSLVRLDLSENCI-------------------MVLPAT 248

  Fly   190 FGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNAL 254
            .|....|..|.|:.|::.||. .:...|..|:.|.||||:|||:. .:|..|..|.:|:||.|:|
plant   249 IGGLISLTRLDLHSNRIGQLP-ESIGDLLNLVNLNLSGNQLSSLP-SSFNRLIHLEELDLSSNSL 311

  Fly   255 DALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVG-LG 318
            ..| |...|:    ::.|::||:..|.|..: .:.....:.::.|....|.:.:|..|  || |.
plant   312 SIL-PESIGS----LVSLKKLDVETNNIEEI-PHSISGCSSMEELRADYNRLKALPEA--VGKLS 368

  Fly   319 SLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHL 383
            :|..|.::||.|.:: |.|.:::.||..||:|:|.||.:.|.:....||.   :||: ||...:|
plant   369 TLEILTVRYNNIRQL-PTTMSSMANLKELDVSFNELESVPESLCYAKTLV---KLNI-GNNFANL 428

  Fly   384 H--PLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLE 437
            .  |....:|..||.|.:.:|:::.|.. .|..:..|:.|....|.|||:..|:.|
plant   429 RSLPGLIGNLEKLEELDMSNNQIRFLPY-SFKTLSNLRVLQTEQNPLEELPRDITE 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	38/130 (29%)
		LRR_8	104..164	CDD:290566	11/38 (29%)
		leucine-rich repeat	106..129	CDD:275380	0/1 (0%)
		leucine-rich repeat	130..153	CDD:275380	7/24 (29%)
		leucine-rich repeat	154..195	CDD:275380	6/40 (15%)
		LRR_RI	194..455	CDD:238064	78/247 (32%)
		LRR_8	194..254	CDD:290566	23/59 (39%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
		leucine-rich repeat	220..243	CDD:275380	11/22 (50%)
		leucine-rich repeat	244..267	CDD:275380	9/22 (41%)
		LRR_8	271..330	CDD:290566	16/59 (27%)
		leucine-rich repeat	272..295	CDD:275380	5/22 (23%)
		leucine-rich repeat	296..319	CDD:275380	7/23 (30%)
		LRR_8	319..380	CDD:290566	22/60 (37%)
		leucine-rich repeat	320..343	CDD:275380	7/22 (32%)
		leucine-rich repeat	344..369	CDD:275380	10/24 (42%)
		LRR_8	368..428	CDD:290566	16/61 (26%)
		leucine-rich repeat	370..393	CDD:275380	7/24 (29%)
		leucine-rich repeat	394..417	CDD:275380	6/22 (27%)
		leucine-rich repeat	418..441	CDD:275380	8/20 (40%)
PIRL5	NP_179336.1	LRR_RI	202..451	CDD:238064	82/281 (29%)
		leucine-rich repeat	206..231	CDD:275380	7/24 (29%)
		LRR_8	207..265	CDD:290566	17/76 (22%)
		leucine-rich repeat	232..254	CDD:275380	6/40 (15%)
		LRR_8	254..334	CDD:290566	31/86 (36%)
		leucine-rich repeat	255..300	CDD:275380	18/46 (39%)
		leucine-rich repeat	301..323	CDD:275380	9/26 (35%)
		leucine-rich repeat	324..346	CDD:275380	5/22 (23%)
		LRR_8	345..403	CDD:290566	20/60 (33%)
		leucine-rich repeat	347..369	CDD:275380	7/23 (30%)
		leucine-rich repeat	370..392	CDD:275380	7/22 (32%)
		leucine-rich repeat	393..440	CDD:275380	17/50 (34%)
		LRR_8	414..474	CDD:290566	18/64 (28%)
		leucine-rich repeat	441..463	CDD:275380	6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2317
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050