DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6749 and RLP19

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_179112.1	Gene:	RLP19 / 815997	AraportID:	AT2G15080	Length:	983	Species:	Arabidopsis thaliana

Alignment Length:	619	Identity:	147/619 - (23%)
Similarity:	225/619 - (36%)	Gaps:	181/619 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 GENADHLANLLDL-DLTGAAPINVHTNGF-----SILPNLRQLNLSGCGLVDIRGNHFAPESALQ 131
            ||....|.:|..| ||.      :.||.|     |.|.||..|.     .:|:..|:|..|
plant   222 GELPSSLGSLFHLTDLI------LDTNHFVGKIPSSLGNLSHLT-----SIDLHKNNFVGE---- 271

  Fly   132 RIDFSHNQMELL------DRDF-------FGNLRKLIYANFSHNALK---QCDLPHMPLLNRLEL 180
             |.||...:..|      |.:.       ||||.:|...|...|.|.   ...|.::..|:.|.|
plant   272 -IPFSLGNLSCLTSFILSDNNIVGEIPSSFGNLNQLDILNVKSNKLSGSFPIALLNLRKLSTLSL 335

  Fly   181 GHNRLV----------------------------NATFGVCPQLQELILNDNQL----------- 206
            .:|||.                            ::.|.: |.|:.:.|.:|||
plant   336 FNNRLTGTLPSNMSSLSNLKLFDATENHFTGPLPSSLFNI-PSLKTITLENNQLNGSLGFGNISS 399

  Fly   207 ------IQLDVNAFRG--------LHGLLELQLSG-NRLSSIGLETFQPLAQLRKLNLSQ-NALD 255
                  ::|..|.|||        |..|.||.||. |....:....|..|..:..||||. |...
plant   400 YSNLTVLRLGNNNFRGPIHRSISKLVNLKELDLSNYNTQGLVDFTIFSHLKSIEYLNLSHLNTTT 464

  Fly   256 ALRPNVFGAVQNFVLHLQQLDLSGNRIRL-----LFDNQFRVLARLQM----------------- 298
            .:  :::..:.:|.| |..|||||:.:..     |.::...::::|.:
plant   465 TI--DMYEILSSFKL-LDTLDLSGSHVSTTNKSSLSNSSLVLISQLYLSGCGITEFPKFLRSQEL 526

  Fly   299 ---LDVSRNSI----------------ASLSPAHFVG------LG--------SLRKLYLQYNAI 330
               ||:|.|.|                .:||...|:|      ||        ::|:|:...|..
plant   527 MLTLDISNNKIKGQVPGWLWMLPVLNYVNLSNNTFIGFERSTKLGLTSIQEPPAMRQLFCSNNNF 591

  Fly   331 LEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHP-LAFSSLPFL 394
            ....|:....|..|.|||.|.|..........|....|.::.|||..||:..|.| ..|.||..|
plant   592 TGNIPSFICELPYLSTLDFSNNKFNGSIPTCMGNIQSPYLQALNLRHNRLSGLLPENIFESLISL 656

  Fly   395 EYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKV- 458
            :   :|||:|.....|..:.:..|..|::..|.:.:.....|.||..:|.:::.:|  .|...:
plant   657 D---VGHNQLVGKLPRSLSHISSLGLLNVESNKISDTFPLWLSSLQELQVLVLRSN--AFYGPIE 716

  Fly   459 NVSFPNLKRVAIEGNPWQ--CPC--FVKLQHWLATRDVVYLRDNTGYYKGERPLCIVTNVDY--- 516
            ...|..|:.:.|.||.:.  .|.  ||   :|.|   :..|.:|.....||....:..:.||
plant   717 KTQFSKLRIIDISGNQFNGTLPANFFV---NWTA---MFSLDENEDQSNGETMSNMYMSTDYFYF 775

  Fly   517 ---CIQN------LQAVRRLGILGDFQGEQVEAD 541
               .:.|      |:.|.::..:.||.|.:.|.:
plant   776 DSMVLMNKGVEMELERVLKVFTVIDFSGNKFEGE 809

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	54/223 (24%)
		LRR_8	104..164	CDD:290566	19/72 (26%)
		leucine-rich repeat	106..129	CDD:275380	6/22 (27%)
		leucine-rich repeat	130..153	CDD:275380	9/35 (26%)
		leucine-rich repeat	154..195	CDD:275380	12/71 (17%)
		LRR_RI	194..455	CDD:238064	83/343 (24%)
		LRR_8	194..254	CDD:290566	25/86 (29%)
		leucine-rich repeat	196..219	CDD:275380	11/47 (23%)
		leucine-rich repeat	220..243	CDD:275380	8/23 (35%)
		leucine-rich repeat	244..267	CDD:275380	5/23 (22%)
		LRR_8	271..330	CDD:290566	22/113 (19%)
		leucine-rich repeat	272..295	CDD:275380	7/27 (26%)
		leucine-rich repeat	296..319	CDD:275380	12/72 (17%)
		LRR_8	319..380	CDD:290566	17/60 (28%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)
		leucine-rich repeat	344..369	CDD:275380	7/24 (29%)
		LRR_8	368..428	CDD:290566	20/60 (33%)
		leucine-rich repeat	370..393	CDD:275380	10/23 (43%)
		leucine-rich repeat	394..417	CDD:275380	6/22 (27%)
		leucine-rich repeat	418..441	CDD:275380	6/22 (27%)
RLP19	NP_179112.1	PLN00113	3..>646	CDD:331614	105/443 (24%)
		leucine-rich repeat	114..137	CDD:275380
		leucine-rich repeat	138..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380	4/10 (40%)
		leucine-rich repeat	234..257	CDD:275380	10/28 (36%)
		leucine-rich repeat	258..281	CDD:275380	8/32 (25%)
		leucine-rich repeat	282..305	CDD:275380	6/22 (27%)
		leucine-rich repeat	306..329	CDD:275380	5/22 (23%)
		leucine-rich repeat	330..351	CDD:275380	6/20 (30%)
		leucine-rich repeat	354..377	CDD:275380	1/23 (4%)
		leucine-rich repeat	378..402	CDD:275380	5/23 (22%)
		leucine-rich repeat	403..424	CDD:275380	5/20 (25%)
		leucine-rich repeat	427..451	CDD:275380	8/23 (35%)
		leucine-rich repeat	452..477	CDD:275380	6/26 (23%)
		leucine-rich repeat	507..526	CDD:275380	1/18 (6%)
		leucine-rich repeat	527..550	CDD:275380	5/22 (23%)
		leucine-rich repeat	551..574	CDD:275380	6/22 (27%)
		leucine-rich repeat	575..604	CDD:275380	5/28 (18%)
		PLN00113	<604..692	CDD:331614	27/90 (30%)
		leucine-rich repeat	605..630	CDD:275380	7/24 (29%)
		leucine-rich repeat	631..655	CDD:275380	10/23 (43%)
		PLN00113	<656..739	CDD:331614	20/87 (23%)
		leucine-rich repeat	656..676	CDD:275380	6/22 (27%)
		leucine-rich repeat	677..700	CDD:275380	6/22 (27%)
		leucine-rich repeat	701..722	CDD:275380	4/22 (18%)
		leucine-rich repeat	723..795	CDD:275380	18/77 (23%)
		leucine-rich repeat	796..819	CDD:275380	4/14 (29%)
		PLN00113	<808..962	CDD:331614	0/2 (0%)
		leucine-rich repeat	820..843	CDD:275380
		leucine-rich repeat	844..867	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910