DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and Lrrc47

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_957678.1 Gene:Lrrc47 / 72946 MGIID:1920196 Length:581 Species:Mus musculus


Alignment Length:380 Identity:113/380 - (29%)
Similarity:159/380 - (41%) Gaps:73/380 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   172 MPLLNRLEL-GHNRLVNATFGVC---PQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLS- 231
            :|||:.||: |...|.....|:.   |||..|:|..|.|                    |..|| 
Mouse    51 LPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNAL--------------------GPGLSP 95

  Fly   232 SIGLETFQPLAQLRKLNLSQNALDALRPNV-FGAVQNFVL-HLQQLDLSGNRIRLLFDNQFRVLA 294
            .:|     ||..||.|:||.|||:.|.|.. .|..:...| .||.|:|||||:|.|..:..|...
Mouse    96 ELG-----PLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAP 155

  Fly   295 RLQMLDVSRNSIASLSPAHF--VGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFL 357
            |||.|:::.|.:.:..|..|  ..|..|.:|....|.:.|:.| ..|.|.:|.|||||.|.|..:
Mouse   156 RLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNCLRELSP-DIAHLASLKTLDLSNNQLTEI 219

  Fly   358 EEQIFGGNTLPRMRRLNLNGNRM--KHLHPL--AFSSLPFLEYLKL--------GHNELKSLDVR 410
            ..::   ...|:::.:|..|||:  |.|..:  ...:...||||:.        |..|....:.|
Mouse   220 PAEL---ADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSILEYLRAGGRGGRSKGRQEASEKEDR 281

  Fly   411 MFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEIL-VDNNRLTFLAKVNVSFPNLKRVAIEGNP 474
               ..||.:|.|......||   :|.:|...:.::| |..|......:|:   |.:|.|    .|
Mouse   282 ---KKRRERKQHRESGEGEE---EVADSARLMLKVLHVSENPTPLTVRVS---PEVKDV----RP 333

  Fly   475 WQCPCFVK---LQHWLATRDVVYLRDNTGYYKGERPLCIV-TNVDYCIQNLQAVR 525
            :.....|:   ||...|.|.  :|...|   |....||.. |.......:|||||
Mouse   334 YIVGAIVRGMDLQPGNALRR--FLNSQT---KLHDDLCEKRTAATIATHDLQAVR 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 29/88 (33%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380 8/26 (31%)
LRR_RI 194..455 CDD:238064 84/278 (30%)
LRR_8 194..254 CDD:290566 19/60 (32%)
leucine-rich repeat 196..219 CDD:275380 5/22 (23%)
leucine-rich repeat 220..243 CDD:275380 6/23 (26%)
leucine-rich repeat 244..267 CDD:275380 11/23 (48%)
LRR_8 271..330 CDD:290566 22/60 (37%)
leucine-rich repeat 272..295 CDD:275380 11/22 (50%)
leucine-rich repeat 296..319 CDD:275380 7/24 (29%)
LRR_8 319..380 CDD:290566 19/60 (32%)
leucine-rich repeat 320..343 CDD:275380 7/22 (32%)
leucine-rich repeat 344..369 CDD:275380 8/24 (33%)
LRR_8 368..428 CDD:290566 18/71 (25%)
leucine-rich repeat 370..393 CDD:275380 6/26 (23%)
leucine-rich repeat 394..417 CDD:275380 7/30 (23%)
leucine-rich repeat 418..441 CDD:275380 6/22 (27%)
Lrrc47NP_957678.1 LRR_RI 34..260 CDD:238064 76/237 (32%)
leucine-rich repeat 54..78 CDD:275380 6/23 (26%)
LRR_8 77..143 CDD:290566 32/90 (36%)
LRR 1 78..97 9/38 (24%)
leucine-rich repeat 79..102 CDD:275380 11/47 (23%)
LRR 2 102..123 10/20 (50%)
leucine-rich repeat 103..132 CDD:275380 12/28 (43%)
LRR 3 132..154 11/21 (52%)
leucine-rich repeat 133..156 CDD:275380 11/22 (50%)
LRR_8 155..239 CDD:290566 27/87 (31%)
LRR 4 156..177 7/20 (35%)
leucine-rich repeat 157..182 CDD:275380 7/24 (29%)
LRR 5 182..204 6/22 (27%)
leucine-rich repeat 183..205 CDD:275380 7/22 (32%)
LRR 6 205..227 8/24 (33%)
leucine-rich repeat 206..228 CDD:275380 8/24 (33%)
LRR 7 228..248 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..301 9/44 (20%)
B3_4 332..504 CDD:214876 17/57 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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