DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and AgaP_AGAP004017

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:XP_001689126.2 Gene:AgaP_AGAP004017 / 5667430 VectorBaseID:AGAP004017 Length:359 Species:Anopheles gambiae


Alignment Length:317 Identity:81/317 - (25%)
Similarity:132/317 - (41%) Gaps:63/317 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 LSGNRLSSIGLETFQ-------PLAQLRKLNLSQNALDALRP--NVFGA---VQNF--VLHLQQL 275
            |:|:.|....|.||.       |:.:   |.:...|:..:.|  :|.|:   :|.:  |||||..
Mosquito    27 LAGSELFVCILSTFDYTPGKDIPVFE---LPVDVKAIRFIEPFSDVHGSDNEIQMYDRVLHLQLN 88

  Fly   276 DLSGNRIRLLFDNQFRVLARLQMLDVSRNSIAS-LSPAHFVGLGSLRKLYLQYNAILEIKPA--T 337
            ......:|........:...|...|.|.|:|.. |.|.:  ...:||.|.|.||..|:...|  .
Mosquito    89 SPEAIELRSSSTRAVEIAPNLAYADFSSNAITEVLVPPN--QSYALRYLDLNYNYRLKHPQALEN 151

  Fly   338 FAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPF-LEYLKLGH 401
            .:.|:||:||.||...:|.:.:.:|  ..|.|:..|.|..|.:|.::   ...||. |..|:|..
Mosquito   152 ISRLVNLETLHLSSCVVETIPQNMF--ENLNRLAHLTLASNNLKQIN---LEQLPMSLTLLRLDV 211

  Fly   402 NELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNVSFPNLK 466
            |.||.......|.:..|:.|:|.||.|:|:|::.|     ||                 :.|.|:
Mosquito   212 NGLKEFLTSEMARLPLLEDLNLEHNELKELNVNAL-----VQ-----------------AAPKLR 254

  Fly   467 RVAIEGNPWQCPCFVKLQHWLATRDVVYLR----------DNTGYYKGERPLCIVTN 513
            ..:|..||.:.|....:...|..|::.|..          ::..:|:|   :|:.::
Mosquito   255 LFSIGRNPLKQPVLNAILDELNRRNIAYYNMEVSSDMQCGEHEVHYRG---VCMASD 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 9/37 (24%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380
LRR_RI 194..455 CDD:238064 69/247 (28%)
LRR_8 194..254 CDD:290566 8/35 (23%)
leucine-rich repeat 196..219 CDD:275380
leucine-rich repeat 220..243 CDD:275380 7/24 (29%)
leucine-rich repeat 244..267 CDD:275380 5/27 (19%)
LRR_8 271..330 CDD:290566 17/59 (29%)
leucine-rich repeat 272..295 CDD:275380 3/22 (14%)
leucine-rich repeat 296..319 CDD:275380 7/23 (30%)
LRR_8 319..380 CDD:290566 22/62 (35%)
leucine-rich repeat 320..343 CDD:275380 9/24 (38%)
leucine-rich repeat 344..369 CDD:275380 8/24 (33%)
LRR_8 368..428 CDD:290566 19/60 (32%)
leucine-rich repeat 370..393 CDD:275380 5/22 (23%)
leucine-rich repeat 394..417 CDD:275380 7/22 (32%)
leucine-rich repeat 418..441 CDD:275380 9/22 (41%)
AgaP_AGAP004017XP_001689126.2 leucine-rich repeat 81..108 CDD:275380 6/26 (23%)
leucine-rich repeat 109..131 CDD:275380 7/23 (30%)
leucine-rich repeat 132..157 CDD:275380 9/24 (38%)
LRR_8 157..238 CDD:290566 28/85 (33%)
leucine-rich repeat 158..181 CDD:275380 8/24 (33%)
leucine-rich repeat 182..203 CDD:275380 6/23 (26%)
leucine-rich repeat 204..227 CDD:275380 7/22 (32%)
leucine-rich repeat 228..252 CDD:275380 11/45 (24%)
leucine-rich repeat 253..271 CDD:275380 5/17 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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