DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6749 and AgaP_AGAP007468

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_001687916.1	Gene:	AgaP_AGAP007468 / 5666871	VectorBaseID:	AGAP007468	Length:	406	Species:	Anopheles gambiae

Alignment Length:	321	Identity:	79/321 - (24%)
Similarity:	139/321 - (43%)	Gaps:	55/321 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 DNQLIQLDVNAFRGLHGLL--ELQLSGNR-LSSIGLE---------TFQPLAQLRKLNLSQNALD 255
            ||.|.::::     ::|::  .|....|| |:.:.:|         |...:.:|.:|.:.|.||.
Mosquito    65 DNTLTEIEI-----VNGVMLRSLVAGTNRHLTRLYVENCLLDRIPPTLSNMIELEELLIMQCALT 124

  Fly   256 ALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQM--LDVSRNSIASLSPAHFVGLG 318
            |||.:|.  |.|  ..|..:||:.||||.||........:|.:  |.::.|.:..|..:.|..:.
Mosquito   125 ALRLDVL--VNN--PKLTTIDLTRNRIRQLFPITTPPKTKLAVTFLGLAANQLERLDMSMFAFMP 185

  Fly   319 SLRKLYLQYNAILEIK---PATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRM 380
            .|.:..::.|.|:..:   |.|:.:|..   |.:|.||:...:.:   ..||..:|.|.|:.|.:
Mosquito   186 ELEQFDVRGNRIVRFEATAPVTYGSLTR---LLVSSNNITQFDTR---NLTLSELRSLYLDDNAL 244

  Fly   381 KHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEI 445
            ..| |..:..||.|.||....|.||.:|:..|.....|..:.:..|::|.|......::..:..|
Mosquito   245 TEL-PTHWGKLPKLIYLGFDRNYLKRVDMSFFGKFPTLTAIFISENIVETIRTSTPITMPELDII 308

  Fly   446 LVDNNRLTFLAKVNVSFPNL----------------------KRVAIEGNPWQCPCFVKLQ 484
            |.::|::..:.....:||.:                      .|:.:||||.:|.....|:
Mosquito   309 LFESNQIVSVNFTGCNFPKMNLVSLTNNRLTTIPPLLQRFSESRLTMEGNPIKCSSMTALK 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	15/64 (23%)
		LRR_8	104..164	CDD:290566
		leucine-rich repeat	106..129	CDD:275380
		leucine-rich repeat	130..153	CDD:275380
		leucine-rich repeat	154..195	CDD:275380
		LRR_RI	194..455	CDD:238064	70/268 (26%)
		LRR_8	194..254	CDD:290566	13/62 (21%)
		leucine-rich repeat	196..219	CDD:275380	3/15 (20%)
		leucine-rich repeat	220..243	CDD:275380	6/34 (18%)
		leucine-rich repeat	244..267	CDD:275380	10/22 (45%)
		LRR_8	271..330	CDD:290566	16/60 (27%)
		leucine-rich repeat	272..295	CDD:275380	9/22 (41%)
		leucine-rich repeat	296..319	CDD:275380	5/24 (21%)
		LRR_8	319..380	CDD:290566	16/63 (25%)
		leucine-rich repeat	320..343	CDD:275380	6/25 (24%)
		leucine-rich repeat	344..369	CDD:275380	6/24 (25%)
		LRR_8	368..428	CDD:290566	18/59 (31%)
		leucine-rich repeat	370..393	CDD:275380	7/22 (32%)
		leucine-rich repeat	394..417	CDD:275380	8/22 (36%)
		leucine-rich repeat	418..441	CDD:275380	4/22 (18%)
AgaP_AGAP007468	XP_001687916.1	LRR_8	88..147	CDD:290566	19/62 (31%)
		leucine-rich repeat	90..112	CDD:275380	3/21 (14%)
		leucine-rich repeat	113..136	CDD:275380	11/26 (42%)
		LRR_8	135..197	CDD:290566	16/61 (26%)
		leucine-rich repeat	137..160	CDD:275380	9/22 (41%)
		leucine-rich repeat	161..186	CDD:275380	5/24 (21%)
		LRR_8	185..244	CDD:290566	16/64 (25%)
		leucine-rich repeat	187..210	CDD:275380	5/22 (23%)
		leucine-rich repeat	211..233	CDD:275380	7/27 (26%)
		LRR_8	232..289	CDD:290566	17/57 (30%)
		leucine-rich repeat	234..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		leucine-rich repeat	281..304	CDD:275380	4/22 (18%)
		leucine-rich repeat	305..327	CDD:275380	4/21 (19%)
		leucine-rich repeat	328..351	CDD:275380	0/22 (0%)
		leucine-rich repeat	352..370	CDD:275380	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910