DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and lrrc4cb

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:XP_005166545.1 Gene:lrrc4cb / 564462 ZFINID:ZDB-GENE-080327-5 Length:631 Species:Danio rerio


Alignment Length:329 Identity:86/329 - (26%)
Similarity:135/329 - (41%) Gaps:76/329 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 GVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALD 255
            ||....:.|.|.|||:..:.|::|:.|..|..||||.|.:.:|.:..|..|..|..|.|..|.|.
Zfish    74 GVSTNTRYLNLQDNQIQVIKVDSFKHLRHLEILQLSRNHIRNIEIGAFNGLTSLNTLELFDNRLT 138

  Fly   256 ALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSL 320
            .: ||  ||                         |..|::|:.|.:..|.|.|:....|..|.||
Zfish   139 TI-PN--GA-------------------------FEYLSKLKELWLRNNPIESIPSDAFSRLPSL 175

  Fly   321 RKLYL-QYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLH 384
            |:|.| :...:..|....|..|.||..|:|...||    :::.....|.|:..|.::||::..:.
Zfish   176 RRLDLGELKRLSYISSGAFQGLSNLRYLNLGMCNL----KEVPNIQPLIRLDELEMSGNQLTVIQ 236

  Fly   385 PLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDN 449
            |.:|..|..|:.|.:.|.::::::...|..:..|::|:|.|                        
Zfish   237 PSSFKGLVHLQKLWMMHAQVQTIERNSFDDLHSLRELNLAH------------------------ 277

  Fly   450 NRLTFLA-KVNVSFPNLKRVAIEGNPWQCPCFVKLQHWLATRDVVYLRDNTGYYKGERPLCIVTN 513
            |.||||. .:.....:|:||.:..|||.|.|.:....|       :||:.           :.||
Zfish   278 NNLTFLPHDLYTPLHHLQRVHLHHNPWNCNCDILWLSW-------WLRET-----------VPTN 324

  Fly   514 VDYC 517
            ...|
Zfish   325 TSCC 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 24/64 (38%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380 2/3 (67%)
LRR_RI 194..455 CDD:238064 68/261 (26%)
LRR_8 194..254 CDD:290566 21/59 (36%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
leucine-rich repeat 220..243 CDD:275380 9/22 (41%)
leucine-rich repeat 244..267 CDD:275380 9/22 (41%)
LRR_8 271..330 CDD:290566 14/59 (24%)
leucine-rich repeat 272..295 CDD:275380 2/22 (9%)
leucine-rich repeat 296..319 CDD:275380 7/22 (32%)
LRR_8 319..380 CDD:290566 19/61 (31%)
leucine-rich repeat 320..343 CDD:275380 7/23 (30%)
leucine-rich repeat 344..369 CDD:275380 6/24 (25%)
LRR_8 368..428 CDD:290566 15/59 (25%)
leucine-rich repeat 370..393 CDD:275380 6/22 (27%)
leucine-rich repeat 394..417 CDD:275380 4/22 (18%)
leucine-rich repeat 418..441 CDD:275380 4/22 (18%)
lrrc4cbXP_005166545.1 LRRNT 48..81 CDD:214470 2/6 (33%)
LRR_8 77..137 CDD:290566 21/59 (36%)
leucine-rich repeat 79..102 CDD:275380 8/22 (36%)
LRR_RI 82..>281 CDD:238064 66/254 (26%)
leucine-rich repeat 103..126 CDD:275380 9/22 (41%)
LRR_8 125..180 CDD:290566 22/82 (27%)
leucine-rich repeat 127..150 CDD:275380 11/50 (22%)
leucine-rich repeat 151..174 CDD:275380 7/22 (32%)
leucine-rich repeat 175..199 CDD:275380 7/23 (30%)
leucine-rich repeat 200..221 CDD:275380 6/24 (25%)
LRR_8 221..280 CDD:290566 16/82 (20%)
leucine-rich repeat 222..245 CDD:275380 6/22 (27%)
leucine-rich repeat 246..269 CDD:275380 4/22 (18%)
leucine-rich repeat 270..291 CDD:275380 9/44 (20%)
LRRCT 302..352 CDD:214507 11/45 (24%)
I-set 355..443 CDD:254352
Ig 372..439 CDD:143165
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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