DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and si:dkey-1j5.4

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_009293145.1	Gene:	si:dkey-1j5.4 / 563949	ZFINID:	ZDB-GENE-130603-91	Length:	357	Species:	Danio rerio

Alignment Length:	349	Identity:	95/349 - (27%)
Similarity:	152/349 - (43%)	Gaps:	81/349 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 DNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQN 267
            |:.::::..|..:.|.|.|        |||:        .::..:.|.:|::.::.|..|...|.
Zfish    55 DSWILKMGENFLQDLPGSL--------LSSV--------PKIESVKLERNSIKSIHPQAFAGAQR 103

  Fly   268 FVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILE 332
            .:|    |:|.||||..:....|:.|..|:.|.:.:|.||:|.|..|:|:.:|.:|.|..||:..
Zfish   104 LML----LNLQGNRISKIPVKGFKDLLNLRFLMLGQNQIANLKPNMFIGMRNLSELDLPLNALTA 164

  Fly   333 IKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYL 397
            :.|..|..|:.|..||||.                          ||::.:.|.||..|..|.:|
Zfish   165 LPPNAFKPLIALKVLDLSL--------------------------NRIQRISPKAFVGLEELLFL 203

  Fly   398 KLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFL-AKVNVS 461
            .:.:|:|||:....|.|:..|:.|.|.:|||..:.:..||.||::||:.|..|.:..| |.|.:.
Zfish   204 NMDNNKLKSIQAGTFGPLTGLEMLVLDNNLLSTLTVSTLEGLSNLQELYVRKNEIESLPADVFLH 268

  Fly   462 FPNLKRVAIEG------------------------NPWQCPCFV-KLQHWLATRDVVYLRDNTGY 501
            .|.|..|.:.|                        |||:|.|.: .|.|:||       :..|.:
Zfish   269 TPKLTHVGLSGNRLHAIDGNMLANMQGLKEVFLHDNPWKCDCSINSLVHYLA-------QTKTNH 326

  Fly   502 YKGERPLCIVTNV--DYCIQNLQA 523
            ...:|..|.....  |..||.|::
Zfish   327 SPRQRLRCASPEEFRDRAIQELKS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	10/52 (19%)
		LRR_8	104..164	CDD:290566
		leucine-rich repeat	106..129	CDD:275380
		leucine-rich repeat	130..153	CDD:275380
		leucine-rich repeat	154..195	CDD:275380
		LRR_RI	194..455	CDD:238064	72/251 (29%)
		LRR_8	194..254	CDD:290566	10/50 (20%)
		leucine-rich repeat	196..219	CDD:275380	3/15 (20%)
		leucine-rich repeat	220..243	CDD:275380	4/22 (18%)
		leucine-rich repeat	244..267	CDD:275380	4/22 (18%)
		LRR_8	271..330	CDD:290566	21/58 (36%)
		leucine-rich repeat	272..295	CDD:275380	8/22 (36%)
		leucine-rich repeat	296..319	CDD:275380	9/22 (41%)
		LRR_8	319..380	CDD:290566	14/60 (23%)
		leucine-rich repeat	320..343	CDD:275380	8/22 (36%)
		leucine-rich repeat	344..369	CDD:275380	5/24 (21%)
		LRR_8	368..428	CDD:290566	18/59 (31%)
		leucine-rich repeat	370..393	CDD:275380	6/22 (27%)
		leucine-rich repeat	394..417	CDD:275380	8/22 (36%)
		leucine-rich repeat	418..441	CDD:275380	9/22 (41%)
si:dkey-1j5.4	XP_009293145.1	LRRNT	21..53	CDD:279764
		leucine-rich repeat	36..54	CDD:275380
		LRR_8	58..114	CDD:290566	17/75 (23%)
		LRR_RI	59..282	CDD:238064	78/268 (29%)
		leucine-rich repeat	80..103	CDD:275380	4/22 (18%)
		LRR_8	103..162	CDD:290566	22/62 (35%)
		leucine-rich repeat	104..127	CDD:275380	9/26 (35%)
		leucine-rich repeat	128..151	CDD:275380	9/22 (41%)
		LRR_8	150..210	CDD:290566	22/85 (26%)
		leucine-rich repeat	152..175	CDD:275380	8/22 (36%)
		leucine-rich repeat	176..199	CDD:275380	11/48 (23%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		LRR_8	222..282	CDD:290566	21/59 (36%)
		leucine-rich repeat	224..247	CDD:275380	9/22 (41%)
		leucine-rich repeat	248..271	CDD:275380	7/22 (32%)
		leucine-rich repeat	272..293	CDD:275380	3/20 (15%)
		LRRCT	304..356	CDD:214507	16/54 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910